N-Succinimidyl 6-Maleimidohexanoate 6-(马来酰亚胺基)己酸琥珀酰亚胺酯

CAS 55750-63-5 MFCD00043043

化学结构图

55750-63-5
SMILES: OS(=O)(=O)C1CC(=O)N(OC(=O)CCCCCN2C(=O)C=CC2=O)C1=O

化学属性

Mol. FormulaC14H16N2O6
Mol. Weight308
Melting Point70-73

别名和识别编码

Chemical NameN-Succinimidyl 6-Maleimidohexanoate
CAS Number55750-63-5
Alfabeta NameSUCCINIMIDYLMALEIMIDOHEXANOATE N6--
MDL NumberMFCD00043043
Synonym N-Succinimidyl 6-maleimidocaproate, N-Succinimidyl 6-maleimidocaproate, N-(-Maleimidocaproyloxy)succinimide 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 6-马来酰亚氨基己酸 N-琥珀酰亚胺酯 N-(ε-马来酰亚胺己酰氧)琥珀酰亚胺 N-Succinimidyl 6-maleimidocaproate, N-Succinimidyl 6-maleimidocaproate, N-(ε-Maleimidocaproyloxy)succinimide EMCS 6-马来酰亚氨基己酸;
Beilstein Registry Number1499815
Reaxys-RN1499815
PubChem Substance ID24880215
Chemical Name Translation6-(马来酰亚胺基)己酸琥珀酰亚胺酯
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分类

  • {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Linkers and Crosslinkers
  • Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Heterobifunctional Cross-Linking Reagents, Linkers and Crosslinkers, Protein Modification, Protein Structural Analysis, Proteomics
  • {SNA} Amine to Sulfhydryl,
  • {SNA} Amine to Sulfhydryl, Building Blocks, Carbonyl Compounds, Chemical Biology,
  • {SNA} Amine to Sulfhydryl, Building Blocks, Carbonyl Compounds, Chemical Biology, Chemical Synthesis, Crosslinkers, Cyclic Imides, Linkers and Crosslinkers, Organic Building Blocks
  • {SNA} Chemical Biology,
  • {SNA} Amine

相关文献及参考

  • Hashida, S., et al., More useful maleimide compounds for the conjugation of Fab' to horseradish peroxidase through thiol groups in the hinge. J. Appl. Biochem. 6 , 56-63, (1984) 摘要
  • Fargeas, C., et al., Synthetic peptide-based enzyme-linked immunosorbent assay for serodiagnosis of visceral leishmaniasis. J. Clin. Microbiol. 34 , 241-248, (1996) 摘要

安全信息

Warnings IRRITANT
WGK Germany3
Hazard Codes Xn Xi
Storage condition 0-10 0-10°C 储存温度 -20°C
Signal word {} {} {} {} {} {TCI}
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
GHS Symbol
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Cyclic Imides - Carbonyl Compounds
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Crosslinking - Protein Modification
  6. Heterobifunctional Cross-Linking Reagents - Crosslinking
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Linkers - Peptide Chemistry
  5. Crosslinkers - Linkers and Crosslinkers

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