GHS Symbol

WGK Germany3

Hazard Codes T,N F,Xn,N T,N,Xn,F

Hazard statements

• H315 Causes skin irritation 会刺激皮肤
• H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
• H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
• H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
• H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
• H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
• H350 May cause cancer 可能致癌
• H331 Toxic if inhaled 吸入中毒
• H311 Toxic in contact with skin 皮肤接触中毒
• H301 Toxic if swallowed 吞食有毒
• H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
• H370 Causes damage to organs 导致器官损伤

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Precautionary statements

• P501 Dispose of contents/container to..… 处理内容物/容器.....
• P308+P313
• P273 Avoid release to the environment. 避免释放到环境中。
• P301+P310
• P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
• P201 Obtain special instructions before use. 使用前获取专门指示。
• P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
• P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
• P405 Store locked up. 上锁保管。
• P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
• P281 Use personal protective equipment as required. 使用所需的个人防护装备。
• P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
• P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
• P331 Do NOT induce vomiting.. 不要催吐。
• P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。

Signal word Danger {} {} {} {} {} {TCI}

RTECSCV9275000

UN Number UN 3077 9/PG 3 3077

Safety Statements

• S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
• S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
• S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
• S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
• S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
• S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签；
• S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
• S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
• S25 Avoid contact with eyes 避免眼睛接触；
• S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
• S33 Take precautionary measures against static discharges 对静电采取预防措施；
• S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；

Risk Statements

• R45 May cause cancer 可能致癌
• R50/53
• R51/53
• R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
• R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
• R11 Highly flammable 非常易燃
• R38 Irritating to skin 刺激皮肤
• R20 Harmful by inhalation 吸入有害
• R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
• R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
• R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
• R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
• R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Packing GroupIII

Hazard Class9

Storage condition 2-8°C {LY} 2-8°C APPROX 4°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

{

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   22,825,1968

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg/56W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   11,892,1951

TYPE O

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,1699,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   15,632,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MOPMA3 Molecular Pharmacology.  (Williams & Wilkins Co., 428 E. Preston St.,
   Baltimore, MD 21202) V.1-    1965-  Volume(issue)/page/year: 4,427,1968

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   1,225,1940

TYPE OF TEST            : DNA repair
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 36 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 290,175,1993

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,532,1981

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2400 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 192,239,1987

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 100 umol/L
REFERENCE :
   CBPCEE Comparative Biochemistry and Physiology, C: Pharmacology, Toxicology
   and Endocrinology. (Elsevier Science, 660 White Plains Rd., Tarrytown, NY
   10591)  V.74-    1983-  Volume(issue)/page/year: 86,399,1987

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1600 mg/kg
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Rodent - mouse Liver
DOSE/DURATION           : 60 umol/L
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 62,947,1979