Folinic Acid 亚叶酸
CAS 58-05-9 MFCD00867488
化学结构图
SMILES: Nc1nc2c(c(=O)[nH]1)N(C=O)C(CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CN2
化学属性
| Mol. Formula | C20H23N7O7 |
|---|---|
| Mol. Weight | 473.444 |
别名和识别编码
| Chemical Name | Folinic Acid |
|---|---|
| MDL Number | MFCD00867488 |
| Chemical Name Translation | 亚叶酸 |
| Synonym | L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (9CI) 菊白葉酸 N5-formyl-tetrahydrofolate 5-formyltetrahydrofolate 5-甲醯-5,6,7,8-四氫葉酸 10-Formyl-7,8-dihydrofolic acid 5-Formyltetrahydropteroylglutamic acid Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, L- (8CI) 5-Formyl-5,6,7,8-tetrahydrofolic acid l-Leucovorin 2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid FOLINIC ACID N5-Formyl-H4F 5-formyl-5,6,7,8-tetrahydrofolate (6R,S)-5-Formyltetrahydrofolate 亚叶酸 5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamicacid Leucal N5-formyl-5,6,7,8-tetrahydrofolate 5-甲酰-5,6,7,8-四氢叶酸 LEUCOVORIN leucoverin levoleucovorin 5-formyltetrahydrofolic acid |
| CAS Number | 58-05-9 |
| EC Number | 200-361-6 |
| LabNetwork Molecule ID | LN01296494 |
| PubChem Substance ID | 135403648 |
| InChI | InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1 |
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相关文献及参考
- [2]. Iqbal MP, et al. Effect of methotrexate and folinic acid on skeletal growth in mice. Acta Paediatr. 2003 Dec;92(12):1438-44.
- [1]. Keshava, C., et al., Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res, 1998. 397(2): p. 221-8.
- [1]. Keshava, C., et al., Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res, 1998. 397(2): p. 221-8.
- [2]. Iqbal MP, et al. Effect of methotrexate and folinic acid on skeletal growth in mice. Acta Paediatr. 2003 Dec;92(12):1438-44.
其他信息
- Sigma Aldrich:58-05-9(sigmaaldrich)
- MOL 文件:58-05-9.mol
- MSDS 信息:(2S)-2-[[4-[(2-Amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid(58-05-9).msds
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