Glabridin 光甘草定

CAS 59870-68-7 MFCD03427694

化学结构图

59870-68-7
SMILES: CC1(C)C=CC2C3OC[C@H](CC=3C=CC=2O1)C1=CC=C(O)C=C1O

化学属性

Mol. FormulaC20H20O4
Mol. Weight324
Melting Point154-155

别名和识别编码

Chemical NameGlabridin
Synonym Glabridin 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-1,3-benzenediol (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl)-1,3-benzenediol Glabridin
MDL NumberMFCD03427694
Beilstein Registry Number7141956
Chemical Name Translation光甘草定
PubChem Substance ID329799990
CAS Number59870-68-7
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分类

  • {SNA} Alcohols and Phenols, Alphabetical, Analytical Standards, Analytical/Chromatography, Chromatography, E - H, Life Sciences Standards, Natural Compounds, Phytopharma Standards, Substance Classification
  • {SNA} Bioactive Small Molecule Alphabetical Index, Flavonoids, Flavonols, and Flavanols, G, Phytochemicals by Chemical Classification, 生物活性小分子, 细胞生物学, 营养研究

相关文献及参考

  • [2]. Chen CT, et al. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway. Environ Toxicol. 2018 Jun;33(6):679-685.
  • [3]. El-Ashmawy NE, et al. Downregulation of iNOS and elevation of cAMP mediate the anti-inflammatory effect of glabridin in rats with ulcerative colitis. Inflammopharmacology. 2018 Apr;26(2):551-559.
  • [1]. Rebhun JF, et al. Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia. 2015 Oct;106:55-61.
  • [1]. Rebhun JF, et al. Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia. 2015 Oct;106:55-61.
  • [2]. Chen CT, et al. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pa

安全信息

Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
WGK Germany3
GHS Symbol
Safety Statements
Precautionary statements

系列性分类

  1. Life Science 生命科学
  2. Nutrition Research 营养研究
  3. Phytochemicals by Chemical Classification - Nutrition Research
  4. Flavonoids, Flavonols, and Flavanols - Phytochemicals by Chemical Classification
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Natural Compounds - Life Sciences Standards
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Phytopharma Standards - Life Sciences Standards
  6. Substance Classification - Phytopharma Standards
  7. Alcohols and Phenols - Substance Classification
  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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