1,2-Bis(Chloromethyl)Benzene 1,2-双(氯甲基)苯

CAS 612-12-4 MFCD00000903

化学结构图

612-12-4
SMILES: ClCc1ccccc1CCl

化学属性

Mol. FormulaC8H8Cl2
Mol. Weight175
Boiling Point239-241
Melting Point51-55
Density1.422
Flash Point107°(224°F)
TSCAYes
Solubility水解

别名和识别编码

Chemical Name1,2-Bis(Chloromethyl)Benzene
Synonym 1,2-Bis(chloromethyl)benzene 1,2-DI(CHLOROMETHYL)BENZENE 1,2-bis(chloromethyl)-benzen 1,2-bis(chloromethyl)benzene 1,2-bis-chloromethyl-benzene < o-Bis(chloromethyl)benzene o-Xylylene dichloride o-xylene dichloride A,A'-DICHLORO-O-XYLENE ALPHA,ALPHA'-二氯邻二甲苯 ALPHA,ALPHA-DICHLORO-2-XYLENE Benzene, 1,2-bis[chloromethyl]- DICHLORO(ALPHA, ALPHA'-)-O-XYLENE O-XYLYLENE CHLORIDE O-XYLYLENE DICHLORIDE alpha,alpha'-Dichloro-o-xylene; o-Xylylene dichloride o-Bis(chloromethyl)benzene o-Xylene, alpha,alpha'-dichloro- o-Xylylene dichloride {} {} {} {} {Chemi à,à'-dichloro-o-xylene 邻二氯亚二甲苯基 邻二氯苄 邻苯二甲基二氯
CAS Number612-12-4
PubChem Substance ID11919
EC Number210-291-8
Beilstein Registry Number2043675
MDL NumberMFCD00000903
Reaxys-RN2043675
Chemical Name Translation1,2-双(氯甲基)苯
InChIKeyFMGGHNGKHRCJLL-UHFFFAOYSA-N
Wiswesser Line NotationG1R B1G
LabNetwork Molecule IDLN00239153
InChIInChI=1S/C8H8Cl2/c9-5-7-3-1-2-4-8(7)6-10/h1-4H,5-6H2
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分类

  • {SNA} Aryl, Building Blocks, C8, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • Aryl, Building Blocks, C8, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks

相关文献及参考

  • Short: III/39
  • Short: III/20b
  • Used in the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid esters: Synthesis, 11, 1157 (1992).

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H302 Harmful if swallowed 吞食有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes 8 C C;Xi
RTECSZE4085000
Precautionary statements
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P312
  • P301+P330+P331
  • P301+P330+P331+P310
  • P302+P352
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S29 Do not empty into drains 不要排入下水道;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R26 Very toxic by inhalation 吸入极毒
  • R34 Causes burns 会导致灼伤
  • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50/53
UN Number 2928 3261 UN 3261 8/PG 2
Packing GroupII
Hazard Class6.1/8
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2263 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555290

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1131 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555290

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#03225

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 191,79,1987

其他信息

  • F:19
  • 邻二氯苄价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0429 α,α'-二氯邻二甲苯 alpha,alpha'-Dichloro-o-xylene 500G 1360元 2014/06/02 D0429 α,α'-二氯邻二甲苯 alpha,alpha'-Dichloro-o-xylene 25G 347元 2010/06/21 154141000 邻二氯苄 alpha,alpha'-Dichloro-o-xylene 98% 100 GR 1211元
  • 用途一:用作医药、农药中间体
  • TCI Shanghai:α、α'-二氯邻二甲苯 alpha,alpha'-Dichloro-o-xylene,>;97.0%(GC)(612-12-4)
  • Alfa Aesar:邻二氯亚二甲苯基,98% o-Xylylene dichloride, 98%(612-12-4)
  • 图谱信息:邻二氯苄(612-12-4)红外图谱(IR1) 邻二氯苄(612-12-4)质谱(MS) 邻二氯苄(612-12-4)核磁图( 13 CNMR) 邻二氯苄(612-12-4)核磁图( 1 HNMR) 邻二氯苄(612-12-4)红外图谱(IR2)
  • Sigma Aldrich:612-12-4(sigmaaldrich)
  • MSDS 信息:1,2-Bis(chloromethyl)benzene(612-12-4).msds
  • color:white to light beige
  • 海关编码:29036990
  • 用途二:用于医药、化工中间体。
  • MOL 文件:612-12-4.mol
  • Acros Organics:alpha,alpha'-二氯邻二甲苯 alpha,alpha'-Dichloro-o-xylene, 98%(612-12-4)

系列性分类


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