Schisandrin A 五味子甲素

CAS 61281-38-7 MFCD00221760

化学结构图

61281-38-7
SMILES: COC1=CC2CCCCC3C=C(OC)C(OC)=C(OC)C=3C=2C(OC)=C1OC

化学属性

Mol. FormulaC24H32O6
Mol. Weight416.56

别名和识别编码

Chemical NameSchisandrin A
Synonym Schisandrin A
Chemical Name Translation五味子甲素
Wiswesser Line NotationL B686&T&J CO1 DO1 EO1 I1 J1 NO1 OO1 PO1
CAS Number61281-38-7
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相关文献及参考

  • [2]. Li WL, et al. Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat. Basic Clin Pharmacol Toxicol. 2012 Feb;110(2):187-92.
  • [1]. Li WL, et al. Inhibitory effects of Schisandrin A and Schisandrin B on CYP3A activity. Methods Find Exp Clin Pharmacol. 2010 Apr;32(3):163-9.
  • [1]. Li WL, et al. Inhibitory effects of Schisandrin A and Schisandrin B on CYP3A activity. Methods Find Exp Clin Pharmacol. 2010 Apr;32(3):163-9.
  • [2]. Li WL, et al. Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat. Basic Clin Pharmacol Toxicol. 2012 Feb;110(2):187-92.

安全信息

GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
RTECSHP1595000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year: 93,41,1980

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Cytochrome P450  (细胞色素P450)

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