Mebhydrolin Napadisylate 美海屈林萘二磺酸盐
CAS 6153-33-9 MFCD00083420
化学结构图
SMILES:
化学属性
| Mol. Formula | C19H20N2.1/2C10H8O6S2 |
|---|---|
| Mol. Weight | 420.53 |
别名和识别编码
| Chemical Name | Mebhydrolin Napadisylate |
|---|---|
| Synonym | Incidal 9-苯甲基-N-甲基-1,2,3,4-四氢-α-咔啉 Diazoline 美海屈林萘二磺酸盐 甲苯咔啉 1,5-萘二磺酸盐 9-苯甲基-N-甲基-1,2,3,4-四氢-α-咔啉 Omeril Mebhydroline 1,5-naphthalenedisulfonate salt; 3-Methyl-9-benzyl-1,2,3,4-tetrahydrocarbolymnaphthalyn-1,5-disulphonate Diazolin Mebhydrolin napadisylate |
| MDL Number | MFCD00083420 |
| CAS Number | 6153-33-9 |
| EC Number | 228-170-3 |
| Chemical Name Translation | 美海屈林萘二磺酸盐 |
| LabNetwork Molecule ID | LN01343381 |
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分类
- {SNA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M, MEA - MES, Neat Compounds
- Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M, MEA - MES, Neat Compounds
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, M, MEA - MES
- {SNA} Analytical Standards, Antihistamines Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
产品应用
- 抗组胺药，H1 组胺受体拮抗剂。
相关文献及参考
- [2]. Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9.
- Merck 14 ,5770
- Merck: 14,5770
- [1]. O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7.
- [1]. O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7.
- [2]. Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 470 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,539,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,850,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,850,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,850,1982
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