O-去甲基美托洛尔 O-去甲基美托洛尔

CAS 62572-94-5 MFCD01657298

化学结构图

62572-94-5
SMILES: CC(C)NCC(O)COC1=CC=C(CCO)C=C1

化学属性

Mol. FormulaC14H23NO3
Mol. Weight253.38

别名和识别编码

Chemical NameBenzeneethanol,4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
CAS Number62572-94-5
Synonym O-Demethylmetoprolol SL 80-0088 H 105/22 (+/-)-O-Demethylmetoprolol 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol (+/-)-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol
Chemical Name TranslationO-去甲基美托洛尔
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分类

  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • A metabolite of Metoprolol.

相关文献及参考

  • Lennard, M.S., et al.: Br. J. Clin. Pharmacol., 14, 713 (1982),
  • Gengo, F.M., et al.: Clin. Pharmacol. Ther., 36, 320 (1984),

安全信息

RTECSDA0512150
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPSDY Pharmacological and Biochemical Properties of Drug Substances.
   (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC
   20037)  V.1-    1977-  Volume(issue)/page/year: 2,186,1979

系列性分类


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