1-Aminopiperidine Hydrochloride N-氨基哌啶盐酸盐

CAS 63234-70-8 MFCD01701508

化学结构图

63234-70-8
SMILES: Cl.NN1CCCCC1

化学属性

Mol. FormulaC5H12N2
Mol. Weight137
Melting Point146-151°
TSCANo

别名和识别编码

Chemical Name1-Aminopiperidine Hydrochloride
CAS Number63234-70-8
Synonym 1-Piperidinamine, monohydrochloride 1-Piperidinamine Monohydrochloride N-Aminopiperidine Hydrochloride 1-Aminopiperidine hydrochloride 1-Piperidinamine Hydrochloride 1-Piperidinamine hydrochloride
MDL NumberMFCD01701508
Chemical Name TranslationN-氨基哌啶盐酸盐
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分类

  • Amines
  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • 1-Aminopiperidine is a metabolite (M1) of the canabinoid receptor 1 antagonist Rimonabant (R517800), an antiobesity agent.

相关文献及参考

  • Hillard, C., et al.: J. Neurochem., 69, 631 (1997),
  • Bisogno, T., et al.: J. Biol. Chem., 272, 3315 (1997),
  • Di Marzo, V., et al.: Life Sci., 65, 645 (1999),

安全信息

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
RTECSTM4250200 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   17,614,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   17,614,1966

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Piperidines 哌啶

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