Geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-,(15R)-
CAS 70563-58-5 MFCD00151702
化学结构图
SMILES: C[C@H]1C=C(C)[C@H](OC(N)=O)[C@H](C=CC=C(C)C(=O)NC2=CC(=O)C=C([C@H](OC)[C@@H](C)C[C@H](OC)[C@@H]1OC)C2=O)OC |c:2,11,13|
化学属性
| Mol. Formula | C30H42N2O9 |
|---|---|
| Mol. Weight | 574.66 |
别名和识别编码
| Chemical Name | Herbimycin A from Streptomyces hygroscopicus |
|---|---|
| MDL Number | MFCD00151702 |
| PubChem Substance ID | 24895756 |
| Beilstein Registry Number | 4834067 |
| Synonym | Antibiotic Tan 420F Herbimycin A from Streptomyces hygroscopicus Herbimycin A |
| CAS Number | 70563-58-5 |
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分类
- {SNA} Anti
- {SNA} Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Antiviral, Benzenoids, Bioactive Small Molecule Alphabetical Index, Chemical Structure Class, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, H, Inhibits an Enzyme, Kinase/Phosphatase Biology, Mechanism of Action, P to Q, Protein Kinase Inhibitors, Protein kinase, tyrosine, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Spectrum of Activity, Tyrosine Kinase (TK), 抗生素, 生化试剂, 生物活性小分子,
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 19 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,1114,1980
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