Acrylic acid 丙烯酸

CAS 79-10-7 MFCD00004367

化学结构图

79-10-7
SMILES: C=CC(=O)O

化学属性

Mol. FormulaC3H4O2
Mol. Weight72.06
Boiling Point139
Density1.051
Melting Point13
Refractive index1.4190 to 1.4220
Autoignition Point744 °F
Vapor Density2.5 (vs air)
Vapor Pressure4 mmHg ( 20 °C)
Flash Point54.44°C
TSCAYes
SolubilitySoluble in water, chloroform, ethanol, methanol, and DMF.
Stability易吸潮,对光线、空气敏感

别名和识别编码

Chemical NameAcrylic acid
CAS Number79-10-7
PubChem Substance ID6581
EC Number201-177-9
Beilstein Registry Number635743
MDL NumberMFCD00004367
Synonym Acrylic acid {LY} Acrylic acid Acrylic acid, glacial Acrylsαure CH2=CHCOOH ETHYLENECARBOXYLIC ACID Ethylenecarboxylic acid Glacial acrylic acid Kyselina akrylova PROPENOIC ACID Propene acid Propenoic acid RARECHEM AL BO 0141 RCRA waste number U008 Vinylformic acid acideacrylique acideacrylique(french) acidoacrilio acrylicacid,[waste] acrylicacid,glacial acrylicacid,inhibited ai3-15717 caswellno.009a {} {LY} Acrylic acid {} {} {LY} Acrylic acid {} {} {} {LY} Acrylic acid {} {} {} {} {LY} Acrylic acid {} {} {} {} {} {LY} Acrylic acid {} {} {} {} {} {} { {} {} {} {} {} {} {LY} Acrylic acid {} {} {} {} {} {} {} {LY} Acrylic acid {} {} {} {} {} {} {} {} {LY} Acryli
Merck Number130
Reaxys-RN635743
Chemical Name Translation丙烯酸
Wiswesser Line NotationQV1U1
LabNetwork Molecule IDLN00195907
InChIInChI=1S/C3H4O2/c1-2-3(4)5/h2H,1H2,(H,4,5)
Canonical SMILESC=CC(O)=O
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分类

  • {SNA} Acrylic Acids and Salts, Acrylic Monomers, Materials Science, Monomers, Polymer Science
  • {SNA} Acrylic Acids and Salts, Acrylic Monomers, Chemical Synthesis, Development Quantities for Research, Monomers, Polymer Science, 材料科学
  • Acrylic Acids and Salts, Acrylic Monomers, Materials Science, Monomers, Polymer Science

产品应用

  • Usually used in preparing monodispersed poly (N-isopropylacryamide) (PNIPAM)/AAc microgels.And also used primarily as an intermediate in the production of acrylates.

相关文献及参考

  • Merck: 14,130
  • Merck: 14,130 Beilstein:2(4)1455

安全信息

GHS Symbol
WGK Germany1
Hazard Codes C,N
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H302+H312+H332
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSAS4375000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P303+P361+P353
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P304+P340+P310
  • P403+P233
Signal word
Packing GroupII
UN Number
Risk Statements
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Class8/3
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37440 mg/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0386-0592

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2912 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   61,189,1987

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37440 mg/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0386-0592

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   28,313,1974

TYPE OF TES

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 51,1632,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 33500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,16,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(10),64,1984

TYPE OF TEST

{hazard_co

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 116 mg/L
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   30,505,1992

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 450 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11,49,1988

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 500 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11,49,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 169 gm/kg
SEX/DURATION            : male 13 week(s) pre-mating
                          female 13 week(s) pre-mating  - 3 week(s) post-birth
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
   Reproductive - Effects on Newborn - physical
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 6,1,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 7329 ug/kg
SEX/DURATION            : female 5-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 51,1632,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 14340 ug/kg
SEX/DURATION            : female 5-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 51,1632,1972

Warnings 危化品目录(2015) 危险化学品

其他信息

  • 丙烯酸的生产方法:乙炔羰化法 乙炔、一氧化碳、水和溶剂四氢呋喃、以卤化镍(见络合催化剂)为催化剂,卤化铜作助催化剂,在160~200℃、4.0~5.5MPa下,通过羰化(见羰基合成)得到丙烯酸:CH≡CH+H2O+CO─→CH2= CHCOOH此法正逐渐被丙烯氧化法所取代。 丙烯腈水解法 丙烯腈在硫酸存在下,进行二次水解再经减压蒸馏可得纯丙烯酸:CH2=CHCN+H2O+H2SO4─→CH2=CHCONH2·H2SO4 CH2=CHCONH2·H2SO4+H2O─→CH2=CHCOOH+NH4HSO4 近年,由于丙烯氨化氧化制丙烯腈工艺迅速发展,为丙烯酸生产提供了廉价的丙烯腈。 丙烯腈水解法 丙烯腈在硫酸存在下,进行二次水解再经减压蒸馏可得纯丙烯酸: CH2=CHCN+H2O+H2SO4─→CH2=CHCONH2·H2SO4 CH2=CHCONH2·H2SO4+H2O─→CH2=CHCOOH+NH4HSO4 近年,由于丙烯氨化氧化制丙烯腈工艺迅速发展,为丙烯酸生产提供了廉价的丙烯腈。 丙烯氧化法 分两步进行:第一步用钼-铋系或锑系催化剂,使丙烯氧化为丙烯醛;第二步用钼-钒-钨系催化剂(见金属氧化物催化剂)使丙烯醛氧化为丙烯酸: CH2=CHCH3+O2─→CH2=CHCHO+H2O CH2=CHCHO+2O2─→CH2=CHCOOH 丙烯、蒸汽和预热空气混合进入第一反应器(见下图),反应温度320~340℃,压力270kPa,反应气不经分离直接送入第二反应器,反应温度280~360℃,压力200kPa。两个反应器均用熔盐作载热体。
  • 刺激数据:皮肤-兔子 500 毫克 重度; 眼睛-兔子 1 毫克 重度 (参考: 丙烯酸)
  • Sigma Aldrich:79-10-7(sigmaaldrich)
  • 储运特性:库房通风低温干燥; 与氧化剂分开储运
  • 外观性质:无色液体,有刺激性气味。
  • 概述:丙烯酸是化学式为CH2=CHCOOH的有机化合物,是最简单的不饱和羧酸,由一个乙烯基和一个羧基组成。纯的丙烯酸是无色澄清液体,带有特征 的刺激性气味。密度1.0511。熔点14℃。沸点140.9℃。酸性较强。有腐蚀性。溶于
  • 敏感性:Air Sensitive
  • MOL 文件:79-10-7.mol
  • 灭火剂:雾状水、二氧化碳、泡沫、干粉
  • vapor pressure:4 mm Hg ( 20 °C)
  • 毒性分级:高毒
  • 概述:丙烯酸是最简单的不饱和羧酸,分子结构为一个乙烯基和一个羧基组成。纯的丙烯酸是无色澄清液体,带有特征 的刺激性气味。密度1.0511。熔点14℃。沸点140.9℃。酸性较强。有腐蚀性。溶于水、乙醇和乙醚。化学性质活泼。易聚合而成透明白色粉末 。还原时生成丙酸。与盐酸加成时生成2-氯丙酸。用于制备丙烯酸树脂等,也用于其他有机合成。由丙烯醛氧化或由丙烯腈水解而得,也可由 乙炔、一氧化碳和水合成,或由乙烯和一氧化碳加压氧化而制得。 丙烯酸可发生羧酸的特征反应,与醇反应也可得到相应的酯类。最常见的丙烯酸酯包括丙烯酸甲酯、丙烯酸丁酯、丙烯酸乙酯和丙烯酸-2-乙基 己酯。 丙烯酸及其酯类自身或与其他单体混合后,会发生聚合反应生成均聚物或共聚物。通常可与丙烯酸共聚的单体包括酰胺类、丙烯腈、含乙烯基 类、苯乙烯和丁二烯等。这类聚合物可用于生产各式塑料、涂层、粘合剂、弹性体、地板擦光剂及涂料。
  • 丙烯酸涂料:丙烯酸涂料主要有热塑性丙烯酸涂料、热固性丙烯酸涂料、高固体份丙烯酸涂料、丙烯酸酯乳胶漆、水稀释丙烯酸树脂涂料。 (1)热塑性丙烯酸涂料主要组分是聚甲基丙烯酸甲酯,但单纯的聚甲基丙烯酸甲酯太脆,且对底材的附着力差,溶剂不易发挥尽,原因是其玻璃化转变温度高。溶剂型热塑性丙烯酸涂料的固体含量太低(体积浓度为12% 左右),进入20世纪70年代后用量急剧下降,代之而发展的是热固性丙烯酸涂料,特别有前途的是高固体份的丙烯酸涂料。 (2)热固性丙烯酸树脂可以提高涂料的不挥发物含量,涂料施工后在固化过程中发生交联。热固性丙烯酸涂料除了有较高的固体份以外,
  • 气味 有较强刺激味。对光敏感。能发烟。在氧存在下极易聚合。能与水、乙醚、乙醇任意混溶。化学性质活泼。易聚合。有腐蚀性。商品常加入一定量阻聚剂作稳定剂。

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