Simethicone 西甲硅油

CAS 8050-81-5 MFCD08050815

化学结构图

8050-81-5
SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O

化学属性

Mol. Weight296.62
Mol. Formula(C2H6OSi)n•SiO2

别名和识别编码

CAS Number8050-81-5
Chemical NameSimethicone
Synonym Aligest Plus Antifoam A DC Antifoam A DC antifoam A Dow Antifoam A Dow Corning Antifoam A Espumisan KS 66 Mylicon Phazyme 125 Q 7-2587 Sentry Simethicone GS Silfoam SE 2 Simethicone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {TRC} SonoRx {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {TRC} Simiticone
Chemical Name Translation西甲硅油
PubChem Substance ID6433516
InChIInChI=1S/C6H18O2Si2.O2Si/c1-7-10(5,6)8-9(2,3)4;1-3-2/h1-6H3;
MDL Number
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分类

  • Aliphatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Simethicone is an oral anti-foaming agent used to reduce bloating, discomfort and pain caused by excess gas in the stomach or intestinal tract. Simethicone is a mixture of polydimethylsiloxane and hyd

相关文献及参考

  • Grinshpan, D., et al.: Pharmaceut. Chem. J., 42, 400 (2008),
  • Agarwal, D., et al.: J. Pharmac., 20, 206 (1988),

安全信息

RTECSVW6200000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
REFERENCE :
   AMSGAO AMA Archives of Surgery.  (Chicago, IL)  V.61-80, 1950-60.  For
   publisher information, see ARSUAX.  Volume(issue)/page/year: 78,220,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AMSGAO AMA Archives of Surgery.  (Chicago, IL)  V.61-80, 1950-60.  For
   publisher information, see ARSUAX.  Volume(issue)/page/year: 78,220,1959

Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P337+P313
  • P337+P317
  • P370+P378
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition +4°C

系列性分类

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