3?-Hydroxy Pravastatin Sodium Salt

CAS 81093-43-8 MFCD81093438

化学结构图

81093-43-8
SMILES: [Na+].CC[C@H](C)C(=O)O[C@H]1CC=CC2=C[C@@H](O)[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@H]21

化学属性

Mol. Weight446.51
Mol. FormulaC23H35NaO7

别名和识别编码

CAS Number81093-43-8
Chemical Name3?-Hydroxy Pravastatin Sodium Salt
Synonym (?R,?R,1S,2R,3S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-?,?,3-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • A metabolite of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin.

相关文献及参考

  • [2]. Shiomi M, et al. Pravastatin sodium, a competitive inhibitor of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases the cholesterol content of newly secreted very-low-density lipoprotein in Watanabe heritable hyperlipidemic rabbits. Metabolism. 1994;43(5):559‐564.
  • Serizawa, N., et al.: J. Antibiot., 36, 604 (1983),
  • [1]. Zhang X, Vernikovskaya DI, Wang X, et al. Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS. Biomed Chromatogr. 2016;30(4):548‐554.
  • [1]. Zhang X, Vernikovskaya DI, Wang X, et al. Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS. Biomed Chromatogr. 2016;30(4):548‐554.
  • [2]. Shiomi M, et al. Pravastatin sodium, a competitive inhibitor of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases the cholesterol content of newly secret

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. HMG-CoA Reductase (HMGCR)  (HMG-CoA还原酶)
  1. Medical Research Areas
  2. Metabolism
  3. Drug Metabolite  (药物代谢物)

相关产品推荐