2-((4-(N-(Thiazol-2-Yl)Sulfamoyl)Phenyl)Carbamoyl)Benzoic Acid 2-[[[4-[(2-噻唑氨基)磺酰基]苯氨基]羰基]苯甲酸
CAS 85-73-4 MFCD00005318
化学结构图
SMILES: OC(=O)C1C=CC=CC=1C(=O)NC1C=CC(=CC=1)S(=O)(=O)NC1=NC=CS1
化学属性
| Mol. Formula | C17H13N3O5S2 |
|---|---|
| Mol. Weight | 403.43 |
| Melting Point | 240 |
| Appearance | 白色或类白色结晶性粉末。熔点198-204℃。微溶于乙醇，几乎不溶于水或氯仿，易溶于盐酸或氢氧化钠溶液，易溶于氨水。 |
别名和识别编码
| Chemical Name | 2-((4-(N-(Thiazol-2-Yl)Sulfamoyl)Phenyl)Carbamoyl)Benzoic Acid |
|---|---|
| Synonym | PHTHALYLSULFATHIAZOLE Phthalazole Phthaloylsulfathiazole AFI-Ftalyl -phthalylsulfanilamido)thiazole Ultratiazol 羧苯甲酰磺胺噻唑 2-(N(sup 4)-Phthalyaminobenzenesulfonamido)th 4'-(2-Thiazolylsulfamoyl)phthalanilic acid PHTHALYLSULFATHIOZOLE Talidine 2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid 2-(N4-Phthalylaminobenzenesulfonamide)thiazole 2-(N(sup 4)-Phthalyaminob Enteramida Sulfaphthalazole PHTHALYLSULPHATHIAZOLE 2-[[[4-[(2-噻唑氨基)磺酰基]苯氨基]羰基]苯甲酸 Sulfacetil PST Sulfathalidine 中文名暂缺(0403停产) 2-[[[4-[(2-THIAZOLYLAMINO)SULFONYL]PHENYLAMINO]CARBONYL]BENZOIC ACID |
| MDL Number | MFCD00005318 |
| CAS Number | 85-73-4 |
| PubChem Substance ID | 87576570 |
| Beilstein Registry Number | 359901 |
| EC Number | 201-627-4 |
| Chemical Name Translation | 2-[[[4-[(2-噻唑氨基)磺酰基]苯氨基]羰基]苯甲酸 |
| Reaxys-RN | 359901 |
| Merck Number | 7377 |
| Wiswesser Line Notation | T5N CSJ BMSWR DMVR BVQ |
| LabNetwork Molecule ID | LN00239360 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Additional Standards, Analytical Standards, Antibiotics Standards, Chemical Structure, Chromatography, Clinical Standards, Others, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
- {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Antibiotics, Chemical Structure, Chromatography,
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibiotics, Chemical Structure, Chromatography, Clinical Standards, Others, P, PER - POLA
- {SNA} Alphabetical Index of Analytical Standards,
安全信息
GHS Symbol
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(12),9,1993
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 920 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944
其他信息
- Sigma Aldrich:85-73-4(sigmaaldrich)
- 酞磺胺噻唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T0703 酞磺胺噻唑 Phthalylsulfathiazole 500G 1320元 2014/06/02 T0703 酞磺胺噻唑 Phthalylsulfathiazole 25G 261元
- 方法一:磺胺噻唑（ST）与苯酐进行酰化反应即得粗PST，经精制得到成品。将ST及苯酐充分混匀，140℃反应1.5h。将所得粗品加入水中，用液碱调节pH至8，全溶后在40℃加活性炭脱色半小时，过滤，滤液用盐酸中和至pH=5-6，过滤，洗涤滤饼，干燥、粉碎得成品PST。
- 图谱信息:酞磺胺噻唑(85-73-4)质谱(MS) 酞磺胺噻唑(85-73-4)红外图谱(IR1) 酞磺胺噻唑(85-73-4)红外图谱(IR2) 酞磺胺噻唑(85-73-4)核磁图( 1 HNMR)
- TCI Shanghai:酞磺胺噻唑 Phthalylsulfathiazole,>;95.0%(T)(85-73-4)
- MOL 文件:85-73-4.mol
- 用途一:磺胺类药，用于细菌性痢疾、细菌性溃疡性肠炎，亦可用于肠道手术后预防感染
- 上游原料:磺胺噻唑
京ICP备2020036287号