7-Chloroquinolin-4-ol 7-氯-4-羟基喹啉

CAS 86-99-7 MFCD00006778

化学结构图

86-99-7
SMILES: Oc1ccnc2cc(Cl)ccc12

化学属性

Mol. FormulaC9H6ClNO
Mol. Weight179.60
Melting Point276-279°C
TSCANo
Appearance 无色针状结晶。熔点276-280℃，微溶于冷水，溶于热水。
Boiling Point302.8°C at 760 mmHg
Flash Point136.9°C

别名和识别编码

Chemical Name7-Chloroquinolin-4-ol
Synonym 7-Chloroquinolin-4-ol {LY} 7-Chloroquinolin-4-ol {} {LY} 7-Chloroquinolin-4-ol {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7-Chloroquinolin-4-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00006778
PubChem Substance ID66593
CAS Number86-99-7
EC Number201-715-2
Reaxys-RN125356
Beilstein Registry Number125356
Chemical Name Translation7-氯-4-羟基喹啉
InChIKeyXMFXTXKSWIDMER-UHFFFAOYSA-N
LabNetwork Molecule IDLN00224839
InChIInChI=1S/C9H6ClNO/c10-6-1-2-7-8(5-6)11-4-3-9(7)12/h1-5H,(H,11,12)
Canonical SMILESOC1=CC=NC2=CC(Cl)=CC=C12
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信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Building Blocks, C8 to C10, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Quinolines
  • {SNA} Building Blocks, C8 to C10, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Quinolines

相关文献及参考

  • Aldrich MSDS 1 , 408:C / Corp MSDS 1 (1), 791:A / FT-NMR 1 (3), 431:A / IR-Spectra (3), 1387:H / IR-Spectra (2), 1209:G / RegBook 1 (2), 2615:O / Structure Index 1 , 412:B:8

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 图谱信息:7-氯-4-羟基喹啉(86-99-7)红外图谱(IR2) 7-氯-4-羟基喹啉(86-99-7)红外图谱(IR1) 7-氯-4-羟基喹啉(86-99-7)质谱(MS)
  • 用途一:医药和染料中间体。可用来合成抗癌症药磷酸氯喹。
  • Sigma Aldrich:86-99-7(sigmaaldrich)
  • MOL 文件:86-99-7.mol
  • Alfa Aesar:7-氯-4-羟基喹啉,98+% 7-Chloro-4-hydroxyquinoline, 98+%(86-99-7)
  • 方法一:在实验室，可加热7-氯-4-羟基喹啉-3-甲酸而得。加热至250-270℃时有大量气泡产生。当气泡停止逸出时，冷却，将反应液倒出，冷后得到固态粗品，再用水重结晶。粗品产率为98%。工业生产可从间氯苯胺出发，经缩合、环合、水解而得7-氯-4-羟基喹啉-3-甲酸，将其与石蜡油一起加热消除，将生成物中上层石蜡油吸去而得7-氯-4-羟基喹啉。
  • 7-氯-4-羟基喹啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1092 7-氯-4-羟基喹啉 7-Chloro-4-hydroxyquinoline 10G 318元 2010/05/25 L07119 7-氯-4-羟基喹啉, 98+% 7-Chloro-4-hydroxyquinoline, 98+% 25g 301元 2010/05/25 L07119 7-氯-4-羟基喹啉, 98+% 7-Chloro-4-hydroxyquinoline, 98+% 100g 839元
  • TCI Shanghai:7-氯-4-羟基喹啉 7-Chloro-4-hydroxyquinoline,>;97.0%(T)(86-99-7)
  • 下游产品:4,7-二氯喹啉
  • 上游原料:矿物油 --> 3-氯苯胺 --> 7-氯-4-羟基喹啉-3-羧酸

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Isoquinolines 异喹啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinaldines 奎纳丁
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinolines 喹啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Quinolines 喹啉
  5. C8 to C10 - Quinolines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Quinolines - Halogenated Heterocycles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Quinolines 喹啉