L-Amino Acid Oxidase from Crotalus adamanteus L-氨基酸氧化酶

CAS 9000-89-9 MFCD00131454

化学结构图

9000-89-9
SMILES:

别名和识别编码

Synonym Aromatic L-amino acid oxidase E.C. 1.4.3.2 L-AAO L-AAO L-Amino acid: oxygen oxidoreductase (deaminating) L-AAO L-Amino acid:oxygen oxidoreductase (deaminating) L-Amino Acid Oxidase from Crotalus adamanteus L-Amino Acid Oxidase from Crotalus atrox (Western Diamondback Rattlesnake) L-Amino acid oxidase L-Amino acid: oxygen oxidoreductase (deaminating) L-Aminooxidase
MDL NumberMFCD00131454
CAS Number9000-89-9
EC Number232-564-0
Chemical Name TranslationL-氨基酸氧化酶
Chemical NameL-Amino Acid Oxidase from Crotalus adamanteus Venom
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分类

  • {SNA} 1.4.x.x Acting on CH-NH2, 1.x.x.x Oxidoreductases, Amino Acid Metabolism, Biochemicals and Reagents, Cell Biology, Enzyme Class Index, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, Metabolomics
  • {SNA} 1.4.x.x Acting on CH-NH2, 1.x.x.x Oxidoreductases, Amino Acid Metabolism, Enzym

产品应用

  • L-amino acid oxidase (LAAO) is used to convert L-amino acids to their corresponding α-keto acids. L-amino acid oxidase, from Sigma, has been used in leucine aminopeptidase (LAP) activity assays.

相关文献及参考

  • Merck 14 ,415

安全信息

RTECSRQ8300000
GHS Symbol
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Signal word Danger
Hazard statements
  • H300+H310+H330
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
Hazard Codes T+
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 储存温度 2-8°C 储存温度 -20°C
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1880 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 1,229,1963

其他信息

  • L-Amino Acid Oxidase is an oligomeric glycoprotein composed of unequal amounts of two different approximately 70 kDa subunits. Three electrophoretically different isozymes occur as different combinations of the two subunits. there are approximately two moles of FAD per mole of holo-enzyme. L-amino acid oxidase catalyzes the oxidative deamination of a number of L-amino acids. The enzyme is absolutely specific for L-isomers. The Aladdin product is prepared according to Wellner and Meister, JBC, 235, 2013, (1960) to the point just prior to crystallization.

系列性分类

  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. General Metabolic Enzymes - Metabolomics
  4. Amino Acid Metabolism - General Metabolic Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 1.x.x.x Oxidoreductases - Enzyme Class Index
  6. 1.4.x.x Acting on CH-NH2 - 1.x.x.x Oxidoreductases

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