• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Analytical Standards, EP Standards, EP Standards E - F, Pharmacopeia Metrological Institutes Standards, 分析/色谱
• {SNA} Biochemicals
• {SNA} Ana
• {SNA} Analytical Standards, Pharmacopeia Metrological Institutes Standards, USP Standards, USP Standards G - H, 分析/色谱
• {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards E - F, Pharmaceutical Standards, Pharmacopeia Standards
• {SNA} Carbohydrates,
• Anticoagulants, Bioactive Small Molecules, Biochemicals and Reagents, Blood, Carbohydrates,
• {SNA} Carbohydrates, Carbohydrates A to Z, Carbohydrates H-L, Core Bioreagents, Polysaccharide,

产品应用

• 生化研究，防止凝血酶原转变成凝血酶。

相关文献及参考

• Merck: 14,4653
• [1]. Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):391-412.
• [2]. Anurag Purushothaman, et al. Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. J Biol Chem. 2016 Jan 22;291(4):1652-63.

安全信息

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >779000 iu/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 23,201,1992

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 1400 units/kg/1W-I
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - changes in potassium
REFERENCE :
   AIMDAP Archives of Internal Medicine.  (AMA, 535 N. Dearborn St., Chicago,
   IL 60610)  V.1-    1908-  Volume(issue)/page/year: 145,1070,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 7 mg/kg/4D
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Blood - hemorrhage
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   244,1831,1980

TYPE OF TEST            : TDLo - Lowest

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 102,156,1951

其他信息

• 几乎无臭。无味。为一种天然多糖，取自猪或牛肠粘液或牛肺。有吸湿性。易溶于水(1g溶于20ml水)，溶于盐水溶液，几乎不溶于乙醇、乙醚、丙酮、氯仿和苯。1%的水溶液pH为6.0-7.5。半数致死量(大鼠，静脉)354mg/kg。