• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Cannabinoids, Core Bioreagents, Fatty Acids and conjugates, Fatty Acyls, Fatty acid amides, Lipids and Related Products, Neurobiology, Neuroscience, Pharmacologicals, Polyunsaturated, Research Essentials, Unsaturated Fatty Acids and Derivatives, 代谢组学, 代谢通路, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 脂类, 脂肪酸代谢
• {SNA} AN-AZ, Bioactive Small Molecules, Biochemicals and Reagents, Cannabinoids,
• {SA} AN-AZ, Bioactive Small Molecules, Biochemicals and Reagents, Cannabinoids, Cell Bi

相关文献及参考

• Derocq, J.M., et al., The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines,. FEBS Lett. 425 , 419-425, (1998) 摘要
• Wartmann, M., The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide,. FEBS Lett. 359 , 133, (1995)
• Szallasi, A., and Di Marzo, V., New perspectives on enigmatic vanilloid receptors. Trends Neurosci. 23 , 491-497, (2000) 摘要
• Schwarz, H., Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. J. Neuroimmunol. 55 , 107, (1994) 摘要
• De Petrocellis, L., The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc. Natl. Acad. Sci. U. S. A. 95 , 8375, (1998)
• Axelrod, J., Cannabinoid receptors and their endogenous agonist, anandamide. Neurochem. Res. 23 , 575, (1998)
• Devane, W.A., et al., Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 , 1946, (1992) 摘要
• Twitchell, W., Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J. Neurophysiol. 78 , 43, (1997) 摘要
• Smart, D., et al., The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). Br. J. Pharmacol. 129 , 227-230, (2000)
• Mackie, K., et al., Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol. Pharmacol. 44 , 498, (1993) 摘要
• Merck 14 ,624

安全信息

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 100 mg/kg
SEX/DURATION            : female 14-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
   Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
   PSYCDE Psychoneuroendocrinology.  (Elsevier Science, 660 White Plains Road
   Tarrytown, NY 10591) V.1-    1975-  Volume(issue)/page/year: 21,157,1996

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 140 ug/kg
SEX/DURATION            : female 15-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Newborn - stillbirth
REFERENCE :
   NLETDU Neuroendocrinology Letters.  (Brain Research Promotion, D-7400,
   Tubingen, Germany) V.1-    1979-  Volume(issue)/page/year: 17,271,1995