1,3-Dichloro-2-Propanol 1,3-二氯-2-丙醇

CAS 96-23-1 MFCD00000951

化学结构图

96-23-1
SMILES: OC(CCl)CCl

化学属性

Mol. FormulaC3H6Cl2O
Mol. Weight129
Refractive index1.4820 to 1.4850
Boiling Point172-176
Density1.351
Melting Point-4
Flash Point74°C(lit.)
TSCAYes
Solubilitysoluble. >=10 g/100 mL at 23 °C

别名和识别编码

Chemical Name1,3-Dichloro-2-Propanol
MDL NumberMFCD00000951
CAS Number96-23-1
Synonym 1 1,3-DICHLORO-2-PROPANOL 1,3-dichloroisopropanol 1,3-二氯-2-丙醇 1,3-二氯丙醇 1,3-二氯丙醇, 98+% 1,3-二氯代甘油 1-二乙基氨基-2-丁炔, 98+% 3-二氯-2-丙醇 A,A'-DICHLORO ALPHA,GAMMA-GLYCERINDICHLOROHYDRIN Dichlorohydrin Enodrin GLYCEROL CHLOROHYDRIN GLYCEROL-ALPHA GLYCEROL-ALPHA,GAMMA-DICHLOROHYDRIN Glycerol alpha,gamma-dichlorohydrin Glycerol-alpha,gamma-dichlorohydrin SYM-GLYCEROL DICHLOROHYDRIN U 25,354 alpha-Dichlorohydrin dichloropropanol sym-Dichloroisopropyl alcohol sym-Glycerol dichlorohydrin Β,Βˊ-二氯代异丙醇 α,α'-Dichlorohydrin, Glycerol-α,γ-dichlorohydrin 二氯丙醇-(2) 二氯异丙醇 二氯甘油
PubChem Substance ID7289
EC Number202-491-9
Beilstein Registry Number1732063
Merck Number3074
Chemical Name Translation1,3-二氯-2-丙醇
Reaxys-RN1732063
Wiswesser Line NotationG1YQ1G
LabNetwork Molecule IDLN00189337
InChIInChI=1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2
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分类

  • {SA} Alcohols, Building Blocks, C2 to C6, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
  • {SNA} Alcohols, Building Blocks, C2 to C6, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds

产品应用

  • 用作乙酸纤维、乙基纤维的溶剂。也是环氧树脂、离子交换树脂、环氧氯丙烷的中间体

相关文献及参考

  • Merck: 14,3074 Beilstein:1,364
  • Merck: 14,3074

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H350 May cause cancer 可能致癌
  • H312 Harmful in contact with skin 皮肤接触有害
  • H301 Toxic if swallowed 吞食有毒
  • H227 Combustible liquid 可燃液体
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUB1400000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P302+P350
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P308+P313
  • P332+P313
  • P337+P313
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Packing GroupII
UN Number 2750 UN 2750 6.1/PG 2 UN2733 UN2750
Risk Statements
  • R10 Flammable 易燃
  • R11 Highly flammable 非常易燃
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R34 Causes burns 会导致灼伤
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R45 May cause cancer 可能致癌
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Hazard Codes 6.1 T T,F
Hazard Class6.1
Storage condition 2-8°C
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4550 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0539378

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 125 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 69,203,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 800 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 2,59,1980

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 92,427,1982

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 30 umol/tube
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   80,73,1991

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 250 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 9,401,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   200,785,1978

Restrict 危险品

其他信息

  • 上游原料:环氧氯丙烷 --> 丙烯酰氯 --> 次氯酸
  • 外观性质:无色液体,微有氯仿气味。
  • F:10
  • Alfa Aesar:1,3-二氯丙醇,98+% 1,3-Dichloro-2-propanol, 98+%(96-23-1)
  • 灭火剂:泡沫、干粉、二氧化碳、砂土
  • MOL 文件:96-23-1.mol
  • 用途三:用作乙酸纤维、乙基纤维的溶剂。也是环氧树脂、离子交换树脂、环氧氯丙烷的中间体。
  • 急性毒性:口服- 大鼠 LD50: 110 毫克/ 公斤; 口服- 小鼠 LD50: 100 毫克/ 公斤
  • Sigma Aldrich:96-23-1(sigmaaldrich)
  • Alfa Aesar:1-二乙基氨基-2-丁炔,98+% 1-Diethylamino-2-butyne, 98+%(6323-82-6)
  • 下游产品:1,3-二氯丙酮 --> 1,2,3-三氯丙烷 --> 碘克沙醇
  • 类别:易燃液体
  • 1,3-二氯丙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0402 1,3-二氯-2-丙醇 1,3-Dichloro-2-propanol 500G 479元 2014/06/02 D0402 1,3-二氯-2-丙醇 1,3-Dichloro-2-propanol 25G 152元 2010/06/21 180182500 1,3-二氯丙醇 1,3-Dichloro-2-propanol 99% 250 ML 509元
  • 方法一:1.由氯丙烯与次氯酸反应而得。2.由甘油在冰醋酸存在的情况下,与氯化氢反应而得。原料消耗定额:甘油796kg/t、氯化氢781.2kg/t、冰醋酸66.2kg/t。
  • 储运特性:包装完整、轻装轻卸; 库房通风、远离明火、高温、与氧化剂分开存放
  • 可燃性危险特性:遇明火、高温、强氧化剂可燃; 高温分解有毒光气气体; 燃烧排放有毒氯化物烟雾
  • Acros Organics:1,3-二氯-2-丙醇 1,3-Dichloro-2-propanol, 99%(96-23-1)
  • 用途一:用于抗病毒药更昔洛韦的合成,用作醋酸纤维、乙基纤维的溶剂,也用于制造环氧树脂、离子交换树脂等
  • 毒性分级:高毒
  • TCI Shanghai:1,3-二氯-2-丙醇 1,3-Dichloro-2-propanol,>;97.0%(GC)(96-23-1)
  • MSDS 信息:1,3-二氯-2-丙醇(96-23-1).msds
  • 水中溶解度:110 g/l 水 (20°C),能与乙醇、乙醚混溶,和大多数常规有机溶剂混溶。有醚样气味。
  • 图谱信息:1,3-二氯丙醇(96-23-1)核磁图( 1 HNMR) 1,3-二氯丙醇(96-23-1)核磁图( 13 CNMR) 1,3-二氯丙醇(96-23-1)红外图谱(IR1) 1,3-二氯丙醇(96-23-1)质谱(MS)
  • 刺激数据:皮肤- 兔子 10 毫克/ 24小时 轻度
  • 用途二:用作醋酸纤维、乙基纤维等的溶剂,也用于有机合成
  • 海关编码:29055910
  • 用途四:用作乙酸纤维、乙基纤维的溶剂。也是环氧树脂、离子交换树脂、环氧氯丙烷的中间体

系列性分类


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