Furfura 糠醛

CAS 98-01-1 MFCD00003229

化学结构图

98-01-1
SMILES: O=Cc1ccco1

化学属性

Mol. FormulaC5H4O2
Mol. Weight96
Density1.16
Refractive index1.5240 to 1.5280
Boiling Point159-161
Melting Point-36
Flash Point59°C(lit.)
TSCAYes
Autoignition Point599 °F
Vapor Density3.31 (vs air)
Vapor Pressure13.5 mmHg ( 55 °C)
Solubility8.3 g/100 mL
Stability对光线和空气敏感

别名和识别编码

Chemical NameFurfura
MDL NumberMFCD00003229
CAS Number98-01-1
EC Number202-627-7
Beilstein Registry Number105755
Synonym Furfurale 2-呋喃甲醛 呋喃甲醛 Furfurole 2-Furancarbonal ALPHA-FURFURALDEHYDE 2-FURFUROL furfurol Furfural 呋喃甲醛,2-呋喃甲醛,α-呋喃甲醛,麸醛具造蚁油,焦粘醛 HPFCHO 糠醛 FURFURALDEHYDE {hazard_co FURFURYL ALDEHYDE 糠醛(2-呋喃甲醛) 2-呋喃甲醛 焦粘醛 呋喃甲醛 2-FURANCARBALDEHYDE 2-呋喃亚甲基醛,ACS ANT OIL 夫喃甲醛 Artificial oil of ants 2-呋喃甲醛, ACS, 98% MIN FURAN-2-CARBOXALDEHYDE α-呋喃甲醛 2-Furylaldehyde FEMA 2489 2-FURANCARBOXYALDEHYDE Furfurol 2-呋喃亚甲基醛,98% Furf
PubChem Substance ID87569875
Merck Number4304
Chemical Name Translation糠醛
Reaxys-RN105755
Wiswesser Line NotationT5OJ BVH
LabNetwork Molecule IDLN00194377
InChIInChI=1S/C5H4O2/c6-4-5-2-1-3-7-5/h1-4H
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分类

  • {SNA} Alphabetical Listings,
  • {SNA} A-D, Alphabetical Listings, E-F, F&F Ingredients in Drum Quantities (25-200 kg), Flavors and Fragrances, Kosher Certified Products
  • {SNA} Aldehydes, Building Blocks, C1 to C6, C4 to C7, Carbonyl Compounds, Chemical Synthesis, Furans, Heterocyclic Building Blocks, Organic Building Blocks
  • {SNA} Alphabetical Listings, Certified Food Grade Products, Certified Natural Products, E - H, E-F, E-G, E-H, Flavors and Fragrances, Follows IFRA Guidelines, Halal Certified Products,
  • {SNA} A-D,

产品应用

  • 检定钴,测定硫酸盐。测定芳香族胺、丙酮、生物碱、植物油和胆 醇的试剂。测定戊糖和多戊糖做标准。合成树脂,精制有机物,硝化纤维溶剂,二氯乙烷萃取剂。

相关文献及参考

  • Merck: 14,4304 Beilstein:17(5)9,292
  • Merck: 14,4304

安全信息

Signal word
GHS Symbol
WGK Germany2
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S1/2 None 上锁保管并避免儿童触及;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P308+P313
  • P304+P340+P310
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P337+P313
  • P403+P233
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P303+P361+P353
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P304+P340
  • P302+P352
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338+P337+P313
  • P308+P311
  • P241+P242+P243
  • P301+P310+P330
  • P405 Store locked up. 上锁保管。
Hazard Codes T T,Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H331 Toxic if inhaled 吸入中毒
  • H301 Toxic if swallowed 吞食有毒
  • H312 Harmful in contact with skin 皮肤接触有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H330 Fatal if inhaled 吸入致命
  • H301+H331
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSLT7000000
Packing GroupII
UN Number
Storage condition 易挥发,密封保存;充氩储存 易挥发,密封保存 2-8°C Air Sensitive
Hazard Class6.1/3
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90125 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR,382,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30900 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR,382,1990

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 370 ppm/6H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,279,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSER

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 ppm/6H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,279,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Gastrointestinal - nausea or vomiting
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academi

{

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 175 ppm/6H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:

TYPE OF TEST

{hazar

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 227,117,1989

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 200 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11,91,1988

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 1700 ug/disc
REFERENCE :
   DFSCDX Developments in Food Science.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1978- Volume(issue)/page/year:
   13,353,1986

{

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 8094 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,205,1978

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 5000 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,75,1992

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 100 ppm
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New Yo

Warnings 危险化学品

其他信息

  • 蒸气压:13.5 mm Hg ( 55 °C)
  • 防护措施:刺激皮肤和粘膜可致流泪和头痛,导致皮肤
  • 防护措施:刺激皮肤和粘膜可致流泪和头痛,导致皮肤呈黄色或脱脂及过敏症。吸入高浓度的糠醛会引起炎症,甚至肺水肿、麻醉。空气中最高容许浓度0.000005或20mg/m3,狗口服LD2300mg/kg。 生产设备、管道要密闭,室内要通风良好,操作时应穿戴防护用具。溅及皮肤时用水冲洗,吸入浓
  • 参考质量标准:FCC,1996;FAO/
  • TCI Shanghai:糠醛 Furfural
  • Hazard Note:Irritant
  • 含量分析:按醛测定法(OT-6)分析。所取试样量为1.5g。计算中的当量因子(e)取48.05。 或按GT-10-4中气相色谱法用非极性柱测定。
  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) 糠醛
  • 爆炸物危险特性:与空气混合可爆
  • 检测方法:GC,NMR
  • {Ch
  • MOL 文件:98-01-1.mol
  • 防护措施:刺激
  • 图谱信息:糠醛(98-01-1)核磁图( 1 HNMR) 糠醛(98
  • 用途三:用作分析试剂
  • 糠醛价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80065818 糠醛;呋喃甲醛;麸醛;人造蚁油;氧茂甲醛 500ml 35元 2011/04/16 F0073 糠醛 Furfural 25G 180元 2011/04/16 F0073 糠醛 Furfural 500G 360元
  • 图谱信息:糠醛(98-01-1)核磁图( 1 HNMR) 糠醛(98-01-1)红外图谱(IR1) 糠醛(98-01-1)红外图谱(IR2) 糠醛(98-01-1)核磁图( 13 CNMR) 糠醛(98-01-1)质谱(MS)
  • 方法二:由富含戊聚糖的农产品废料,如玉米芯、棉籽壳、稻糠和甜菜渣等用稀酸水解、脱水并蒸馏而得。
  • Alfa
  • 有特殊的苯甲醛气味,能随水蒸气挥发,极易溶于醇和醚,易溶于热水,丙酮,溶于苯,氯仿。可溶于11份水。易燃。中等毒,半数
  • 用途五:GB 2760—96规定为允许使用的食品用香料;萃取溶剂。主要用于配制各种热加工型香精,如面包、奶油硬糖、咖啡等香精。
  • 用途七:检定钴,测定硫酸盐。测定芳香族胺、丙酮、生物碱、植物油和胆 醇的试剂。测定戊糖和多戊糖做标准。合成树脂,精制有机物,硝化纤维溶剂,二氯乙烷萃取剂。
  • 下游产品:糠醇 --> 呋喃 --> 2-甲基呋喃 --> 2-甲基-3-羟基-4-吡喃酮 --> 5-硝基糠醛 --> 乙基麦芽酚 --> 3(2-呋喃)丙酸 --> 5-硝基-2-糠酸 --> 5-硝基糠醛二乙酸酯 --> 2-呋喃丙酸乙酯 --> 四氢糠醇 --> 5-乙基-2-糠醛 --> 2-甲
  • 蒸气密度:3.31 (vs air)
  • 方法三:糠醛最初从砻糠中得到,农副产品中多含多缩戊糖经水解脱水即生成糠醛。许多农作物的茎,皮,仔壳都含有多缩戊糖,因此都能用作制造糠醛的原料。生产时,将玉米芯,棉子壳或甘蔗渣等原料用硫酸和水蒸气处理,然后经水蒸气蒸馏,分层,减压蒸馏,即可得纯度达99%的产品。糠醛的收离与原料,酸的种类和浓度及其他条件有关,通常与理论收率相差较大。工业上制造糠醛主要有两种方法。加压法适合大规模生产,将原料与稀硫酸在加压下蒸煮,用高压或过热蒸汽带出反应产物,经分馏后得糖醛成品;常压法是将原料与食盐等无机盐及及稀硫酸共煮并同时蒸出糠醛。
  • Alfa Aesar:2-呋喃甲醛,ACS,98%min 2-Furaldehyde
  • 毒性:LD 50 65mg/kg(大鼠,经口)。 ADI尚未规定(FAO/WHO,1994)。

系列性分类


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