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• 试剂商城
• 直接询价

分类

• {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
• {SNA} Building Blocks, C-H Activation, C6, Catalysis and Inorganic Chemistry, Chemical Synthesis,
• {SNA} Building Blocks, C-H Activation, C6, Catalysis and Inorganic Chemistry, Chemical Synthesis, Heterocyclic Building Blocks, Ligands and Auxiliaries, Pyridines
• {SNA} Analytical Reagents,
• {SNA} Analytical Reagents for General Use, Mass Spectrometry (MS), Matrix Substances for MALDI-MS, O-P, Puriss p.a., Puriss p.a., Spectroscopy, 分析/色谱, 分析试剂
• {SNA} Building Blocks,

产品应用

• 有机合成中间体。

相关文献及参考

• Amino groups can be protected, by DCC coupling, as picolinamides, which can be cleaved with acidic Cu(OAc)2: Synth. Commun., 383 (1972).
• Has been found to accelerate significantly oxidations with chromic acid: J. Am. Chem. Soc., 98, 1026 (1976).
• Merck: 14,7403
• Merck: 14,7403 Beilstein:22,33
• [1]. E.G. Romanowski, et al. A Novel Topical Antiviral Agent, PCL–016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model. ARVO Annual Meeting Abstract. May 2005 Volume 46, Issue 13.

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 562 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 487 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other Enzymes
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 23,1343,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other Enzymes
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 17,2377,1969

其他信息

• 用途二:有机合成中间体。
• 检测方法:HPLC,NMR
• 用途一:2-甲基吡啶 高锰酸钾
• 下游产品:2-氨基-4-氯吡啶 --> 2-氨基-4-羟基吡啶 --> 4-氯吡啶-2-甲酰胺 --> 3-溴-2-吡啶羧酸 --> 2-吡啶甲酰肼 --> 4-氯-3-乙基-1-甲基吡唑-5-羧酸乙酯 --> 4-碘吡啶-2-羧酸 --> 吡啶-2-甲酰氯盐酸盐
• Acros Organics:2-吡啶甲酸 Picolinic acid, 99%(98-98-6)
• 方法一:将50g2-甲基吡啶加入2500ml水中，加热搅拌，加入90g高锰酸钾，约1h后再加入第二份90g高锰酸钾。补加500ml水并继续加热2-2.5h，直至紫色消失。冷却，滤出二氧化锰沉淀，用热水洗涤。将滤液减压浓缩，过滤。浓缩液用浓盐酸酸化至刚果红酸性后蒸发至干，将其与250ml95%乙醇检煮回流1h。过滤，滤饼用95%乙醇提取，合并乙醇滤液及提取液，通入干燥的氯化氢，至晶体开始析出为止。冷却至10℃，再通氯化氢至馏和，滤出吡啶甲酸盐酸盐，干燥后得43-44g（盐酸盐熔点210-212℃）。
• 2-吡啶甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010186 2-吡啶甲酸 100g 280元 2011/04/16 P0421 吡啶甲酸 Pyridine-2-carboxylic Acid 25G 230元 2011/04/16 P0421 吡啶甲酸 Pyridine-2-carboxylic Acid 500G 1650元
• MOL 文件:98-98-6.mol
• Alfa Aesar:吡啶2-甲酸,99% 2-Picolinic acid, 99%(98-98-6)
• 图谱信息:2-吡啶甲酸(98-98-6)红外图谱(IR1) 2-吡啶甲酸(98-98-6)核磁图( 13 CNMR) 2-吡啶甲酸(98-98-6)质谱(MS) 2-吡啶甲酸(98-98-6)红外图谱(IR2) 2-吡啶甲酸(98-98-6)核磁图( 1 HNMR)
• 海关编码:29333999
• Sigma Aldrich:98-98-6(sigmaaldrich)
• 水中溶解度:887 g/L (20°C)，溶于乙醇(63 g/l), 易溶于冰乙酸,几乎不溶于乙醚、氯仿和二硫化碳。
• 上游原料:乙醇 --> 高锰酸钾 --> 二氧化锰 --> 直接红 28
• MSDS 信息:2-Pyridinecarboxylic acid(98-98-6).msds
• TCI Shanghai:2-吡啶甲酸 Picolinic Acid,>;99.0%(T)(98-98-6)