Hydroxyhomosildenafil 5-(2-乙氧基-5-((4-(2-羟乙基)哌嗪-1-基)磺基)苯基)-1-甲基-3-丙基-1,6-二氢-7H-吡唑啉[4,3-d]嘧啶-7-酮

CAS 139755-85-4 MFCD39755854

化学结构图

139755-85-4
SMILES: CN1N=C(CCC)C2NC(=NC(=O)C1=2)C1=CC(=CC=C1OCC)S(=O)(=O)N1CCN(CCO)CC1

化学属性

Mol. Weight504.6
Mol. FormulaC23H32N6O5S
Melting Point183-185

别名和识别编码

CAS Number139755-85-4
Chemical NameHydroxyhomosildenafil
Synonym 5-[2-Ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one Lodenafil
Chemical Name Translation5-(2-乙氧基-5-((4-(2-羟乙基)哌嗪-1-基)磺基)苯基)-1-甲基-3-丙基-1,6-二氢-7H-吡唑啉[4,3-d]嘧啶-7-酮
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分类

  • Aromatics
  • Drug Analogues
  • Heterocycles
  • Sulfur & Selenium Compounds

产品应用

  • A Sildenafil (S435000) analog, enhances male sexual function

相关文献及参考

  • Antunes, J., et al.: Bioorg. Med. Chem., 16, 7599 (2008),
  • Toque, H., et al.: Eur. J. Pharmacol., 591, 189 (2008),
  • [1]. Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591(1-3):189-95.

安全信息

GHS Symbol
Safety Statements
Precautionary statements

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Phosphodiesterase (PDE)  (磷酸二酯酶)

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