Amlodipine Diethyl Ester
CAS 140171-65-9 MFCD40171659
化学结构图
SMILES: CC1NC(COCCN)=C(C(C=1C(=O)OCC)C1=CC=CC=C1Cl)C(=O)OCC
化学属性
| Mol. Weight | 423 |
|---|---|
| Mol. Formula | C21H27ClN2O5·C4H4O4 |
| Melting Point | 106-108 |
别名和识别编码
| CAS Number | 140171-65-9 |
|---|---|
| Chemical Name | Amlodipine Diethyl Ester |
| Synonym | 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Diethyl Ester 3-Ethyl 5-Ethyl 4-(2-Chlorophenyl)-6-methyl-2-[[2- [(2-aminoethoxy)methyl]-1,4-dihydr Amlodipine EP Impurity E ; Amlodipine USP Related Compound E |
| Chemical Name Translation | |
| MDL Number | N/A |
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分类
- Aromatics
- Heterocycles
- Intermediates
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Amlodipine Besilate (A633500) impurity.
相关文献及参考
- Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988),
- Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003),
- Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P312
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