Talabostat
CAS 149682-77-9 MFCD49682779
化学结构图
SMILES: CC(C)C(N)C(=O)N1CCCC1B(O)O
别名和识别编码
| Chemical Name | VAL-BORO-PRO |
|---|---|
| PubChem Substance ID | 6918572 |
| InChI | InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1 |
| Synonym | L-valinyl-L-boroproline PT 100 PT-100 PT100 cpd talabostat valinyl-boroproline |
| LabNetwork Molecule ID | LN01346451 |
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相关文献及参考
- [2]. Connolly BA, et al. Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potencyand in vivo efficacy and safety. J Med Chem. 2008 Oct 9;51(19):6005-13.
- [3]. Talabostat
- [4]. Adams S, et al. PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism. Cancer Res. 2004 Aug 1;64(15):5471-80.
- [1]. Lankas GR, et al. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes. 2005 Oct;54(10):2988-94.
- [1]. Lankas GR, et al. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes. 2005 Oct;54(10):2988-94.
- [2]. Connolly BA, et al. Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potencyand in vivo e
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