PF-06840003 3-(5-氟-1H-吲哚-3-基)-2,5-吡咯烷二酮

CAS 198474-05-4 MFCD98474054

化学结构图

198474-05-4
SMILES:

化学属性

Mol. FormulaC12H9FN2O2

别名和识别编码

Chemical NamePF-06840003
Chemicalbook IDCB12523559
Chemical Name Translation3-(5-氟-1H-吲哚-3-基)-2,5-吡咯烷二酮
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相关文献及参考

  • [2]. Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J Med Chem. 2017 Dec 14;60(23):9617-9629.
  • [1]. Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr4863.
  • [1]. Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr4863.
  • [2]. Indoleamine 2

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Halogenated 卤化物 (氟氯溴碘)
  5. Fluoro 氟化物
  1. Medical Research Areas
  2. Metabolism
  3. Indoleamine 2,3-Dioxygenase (IDO)  (吲哚胺 2,3 双加氧酶)

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