Atazanavir 阿扎那韦

CAS 198904-31-3 MFCD98904313

化学结构图

198904-31-3
SMILES: CC(C)(C)[C@H](NC(=O)OC)C(=O)N[C@@H](CC1C=CC=CC=1)[C@@H](O)CN(CC1C=CC(=CC=1)C1C=CC=CN=1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C

化学属性

Mol. Weight705
Mol. FormulaC38H52N6O7

别名和识别编码

CAS Number198904-31-3
Chemical NameAtazanavir
Synonym 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl Ester (3S,8S, 9S, 12S)-2,5,6,13-Pentaazatetradecanedioic Acid BMS-232632 CGP-73547
Chemical Name Translation阿扎那韦
LabNetwork Molecule IDLN01272250
MDL Number
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分类

  • Chiral Reagents
  • Inhibitors
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral.

相关文献及参考

  • [2]. Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96.
  • [3]. Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.
  • Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004),
  • Nolan, D., et al.: Drugs, 63(23), 2555 (2003),
  • Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998),
  • [1]. Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.
  • [1]. Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.
  • [2]. Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96.
  • [3]. Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical tri

系列性分类


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