(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide (Z)-2-((呋喃-2-基甲基)亚磺酰基)-N-(4-((4-(哌啶-1-基甲基)吡啶-2-基)氧基)丁-2-烯-1-基)乙酰胺

CAS 206449-93-6 MFCD06449936

化学结构图

206449-93-6
SMILES:

化学属性

Mol. Weight431.55
Mol. FormulaC22H29N3O4S

别名和识别编码

CAS Number206449-93-6
Chemical Name(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide
Synonym 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide Lafutidine FRG 8813 Laflutidine Protecadin Stogar
Chemical Name Translation(Z)-2-((呋喃-2-基甲基)亚磺酰基)-N-(4-((4-(哌啶-1-基甲基)吡啶-2-基)氧基)丁-2-烯-1-基)乙酰胺
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分类

  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.

相关文献及参考

  • Ajioka, H., et al.: Pharmacology, 61, 83 (2000),
  • Onodera, S., et al.: Jpn. J. Pharmacol., 68, 161 (1995),
  • Umeda, M., et al.: J. Gastroenterol. Heoatol., 14, 859 (1999),
  • [1]. Hirakawa N, et al. A novel histamine 2(H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings. Chem Pharm Bull (Tokyo). 1998;46(4):616-622.

系列性分类


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