AN-7

CAS 213262-83-0 MFCD13262830

化学结构图

213262-83-0
SMILES: CCCC(=O)OCOP(=O)(OCC)OCC

化学属性

Mol. Weight254.21732
Appearance Solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical NameAN-7
FormulaC9H19O6P
Synonym AN7; AN-7; AN 7; butyroyloxymethyl diethylphosphate
IUPAC Namebutyroyloxymethyl diethylphosphate
InChIKeyUGIGKLCVADLBRB-UHFFFAOYSA-N
InChIInChI=1S/C9H19O6P/c1-4-7-9(10)12-8-15-16(11,13-5-2)14-6-3/h4-8H2,1-3H3
Canonical SMILESO=P(OCC)(OCOC(CCC)=O)OCC
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产品应用

  • AN-7 is a potent HDAC inhibitor, is also a prodrug of butyric acid, which induced histone hyperacetylation and differentiation and inhibited proliferation of human prostate 22Rv1 cancer cells in vitro and in vivo. AN-7 is likely to display a high therapeutic index and may be beneficial for prostate cancer patients.

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Medical Research Areas
  2. Epigenetics
  3. HDAC
  1. Medical Research Areas
  2. Neuronal Signaling
  3. HDAC

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