Glutarimide, 2-(1-benzyl-4-piperidyl)-2-phenyl-, (-)-

CAS 21888-99-3 MFCD21888993

化学结构图

21888-99-3
SMILES:

化学属性

Mol. Weight362.51
Mol. FormulaC23H26N2O2

别名和识别编码

Chemical NameGlutarimide, 2-(1-benzyl-4-piperidyl)-2-phenyl-, (-)-
Synonym l-Benzetimide Levetimide (-)-Benzetimide laevo-Benzetimide (3,4'-Bipiperidine)-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, (R)-
Beilstein Registry Number6490018
CAS Number21888-99-3
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相关文献及参考

  • [1]. DeHaven-Hudkins DL, et al. Binding of dexetimide and levetimide to [3H](+)pentazocine- and [3H]1,3-di(2-tolyl)guanidine-defined sigma recognition sites. Life Sci. 1991;49(18):PL135-9.

安全信息

RTECSMA4029500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38500 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,1365,1971

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. mAChR  (毒蕈碱型乙酰胆碱受体)

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