(R)-1-(5-Chloro-2-(2-(4-(4-Fluorobenzyl)-2-Methylpiperazin-1-Yl)-2-Oxoethoxy)Phenyl)Urea Hydrochloride (R)-1-(5-氯-2-(2-(4-(4-氟苄基)-2-甲基哌嗪-1-基)-2-氧代乙氧基)苯基)脲盐酸盐

CAS 288262-96-4 MFCD88262964

化学结构图

288262-96-4
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别名和识别编码

Chemical Name Translation(R)-1-(5-氯-2-(2-(4-(4-氟苄基)-2-甲基哌嗪-1-基)-2-氧代乙氧基)苯基)脲盐酸盐
Chemical Name(R)-1-(5-Chloro-2-(2-(4-(4-Fluorobenzyl)-2-Methylpiperazin-1-Yl)-2-Oxoethoxy)Phenyl)Urea Hydrochloride
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相关文献及参考

  • [2]. Anders HJ, et al. A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. J Clin Invest. 2002 Jan;109(2):251-9.
  • [3]. Furuichi K, et al. Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury. J Immunol. 2008 Dec 15;181(12):8670-6.
  • [4]. Horuk R, et al. A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection. J Biol Chem. 2001 Feb 9;276(6):4199-204.
  • [1]. Liang M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem. 2000 Jun 23;275(25):19000-8.
  • [1]. Liang M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem. 2000 Jun 23;275(25):19000-8.
  • [2]. Anders HJ, et al. A chemokine receptor CCR-1 antagonist reduces renal fi

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. CCR  (趋化因子受体)

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