GW-803430
CAS 515141-51-2 MFCD15141512
化学结构图
SMILES: COc1cc(ccc1OCCN1CCCC1)-[n]1c[n]c2cc([s]c2c1=O)-c1ccc(Cl)cc1
化学属性
| Mol. Weight | 481.99 |
|---|---|
| Mol. Formula | C25H24ClN3O3S |
别名和识别编码
| Synonym | 6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one 6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one GW-3430 GW-803430A GW-3430 GW-803430A |
|---|---|
| CAS Number | 515141-51-2 |
| InChIKey | MWULMTACIBZPGN-UHFFFAOYSA-N |
| Chemical Name | GW-803430 |
| Chemical Name Translation |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, G, GlaxoSmithKline, Hormones, Obesity Research, Orexin, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, G, GlaxoSmithKline, Hormones, Obesity Research, Orexin
相关文献及参考
- [2]. Velusami CC, et al. Effect of Nelumbo nucifera Petal Extracts on Lipase, Adipogenesis, Adipolysis, and Central Receptors of Obesity. Evid Based Complement Alternat Med. 2013;2013:145925.
- Gehlert DR, Rasmussen K, Shaw J, Li X, Ardayfio P, Craft L, Coskun T, Zhang HY, et al., Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression. J. Pharmacol. Exp. Ther. 2 , 429-38, (2009)
- Millan MJ, Gobert A, Panayi F, Rivet JM, Dekeyne A, Brocco M, Ortuno JC, Di Cara B., The melanin-concentrating hormone1 receptor antagonists, SNAP-7941 and GW3430, enhance social recognition and dialysate levels of acetylcholine in the frontal cortex of rats. Int. J. Neuropsychopharmacol. 8 , 1105-22, (2008)
- Smith DG, Davis RJ, Rorick-Kehn L, Morin M, Witkin JM, McKinzie DL, Nomikos GG, Gehlert DR., Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stres
安全信息
GHS Symbol
- P305+P351+P338
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
- R22 Harmful if swallowed 吞咽有害
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