JNJ-10198409 3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基)苯基胺
CAS 627518-40-5 MFCD27518405
化学结构图
SMILES: COC1=CC2CC3=C(NN=C3NC3=CC(F)=CC=C3)C=2C=C1OC
化学属性
| Mol. Weight | 325.34 |
|---|---|
| Mol. Formula | C18H16FN3O2 |
别名和识别编码
| Synonym | 3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine 3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine RWJ 540973 N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine RWJ 540973 |
|---|---|
| CAS Number | 627518-40-5 |
| Chemical Name | JNJ-10198409 |
| PubChem Substance ID | 329815736 |
| Chemical Name Translation | 3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基)苯基胺 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, J, Johnson & Johnson, Kinase/Phosphatase Biology, Platelet Derived Growth Factor Receptor (PDGFR), Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, J, Johnson & Johnson, Kinase/Phosphatase Biology, Platelet Derived Growth Factor Receptor (PDGFR), Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors
相关文献及参考
- Ho, C.Y., et al., (6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: platelet-derived growth factor receptor tyrosine kinase inhibitors with broad antiproliferative activity against tumor cells J. Med. Chem. 48 , 8163-8173, (2005) 摘要
- D'Andrea, M.R., et al. , Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis Mol. Cancer Ther. 4 , 1198-1204, (2005) 摘要
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