4-(3,5-dibromo-4-methoxybenzyl)-6-methyl-2-(methylimino)-2,6-dihydroimidazo[4,5-d]azepin-5(3H)-one 4-(3,5-二溴-4-甲氧基苄基)-6-甲基-2-(甲基亚氨基)-2,6-二氢咪唑并[4,5-d]氮杂-5(3H)-酮

CAS 634151-15-8 MFCD34151158

化学结构图

634151-15-8
SMILES: CNC1=NC2=C(CC3=CC(Br)=C(OC)C(Br)=C3)C(=O)N(C)C=CC2=N1

化学属性

Mol. Weight468.14
Mol. FormulaC17H16Br2N4O2

别名和识别编码

CAS Number634151-15-8
Chemical Name4-(3,5-dibromo-4-methoxybenzyl)-6-methyl-2-(methylimino)-2,6-dihydroimidazo[4,5-d]azepin-5(3H)-one
Synonym 4-[(3,5-Dibromo-4-methoxyphenyl)methyl]-6-methyl-2-(methylamino)imidazo[4,5-d]azepin-5(6H)-one
Chemical Name Translation4-(3,5-二溴-4-甲氧基苄基)-6-甲基-2-(甲基亚氨基)-2,6-二氢咪唑并[4,5-d]氮杂-5(3H)-酮
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分类

  • Heterocycles
  • Nucleotides
  • Bases & Related Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • An antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea.

相关文献及参考

  • [2]. Nodwell M, et al. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. J Org Chem. 2009 Feb 6;74(3):995-1006.
  • [3]. Pan X, et al. Synthesis and cytotoxicity of novel imidazo[4,5-d]azepine compounds derived from marine natural product ceratamine A. Bioorg Med Chem Lett. 2018 Mar 1;28(5):866-868.
  • ########
  • [1]. Manzo E, et al. Ceratamines A and B, antimitotic heterocyclic alkaloids isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Org Lett. 2003 Nov 27;5(24):4591-4.
  • [1]. Manzo E, et al. Ceratamines A and B, antimitotic heterocyclic alkaloids isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Org Lett. 2003 Nov 27;5(24):4591-4.
  • [2]. Nodwell M, et al. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. J Org Chem. 2009 Feb 6;74(3):995-1006.
  • [3]. Pan X, et al. Synth

系列性分类

  1. Medical Research Areas
  2. Cytosketetal Signaling
  3. Microtubule/Tubulin  (微管/微管蛋白)

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