Olmesartan Lactone Impurity Olmesartan杂质2(奥美沙坦酯EP杂质B)

CAS 849206-43-5 MFCD49206435

化学结构图

849206-43-5
SMILES: CCCC1=NC2=C(C(=O)OC2(C)C)N1CC1C=CC(=CC=1)C1C=CC=CC=1C1=NNN=N1

化学属性

Mol. Weight428
Mol. FormulaC24H24N6O2

别名和识别编码

CAS Number849206-43-5
Chemical NameOlmesartan Lactone Impurity
Synonym 3,6-Dihydro-6,6-dimethyl-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-4H-Furo[3,4-d]imidazol-4-one
Chemical Name TranslationOlmesartan杂质2(奥美沙坦酯EP杂质B)
MDL Number
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分类

  • Aromatics
  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A cyclic ester impurity of Olmesartan (O550000).

相关文献及参考

  • [2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.
  • [1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.
  • [1]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.
  • [2]. Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Angiotensin Receptor  (血管紧张素受体)

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