2-(2-Chloro-4-Fluorobenzyl)-3-(4-Fluorophenyl)-7-(Trifluoromethyl)-2H-Indazole 2-(2-氯-4-氟苄基)-3-(4-氟苯基)-7-(三氟甲基)-2H-吲唑

CAS 875787-07-8 MFCD75787078

化学结构图

875787-07-8
SMILES:

化学属性

Mol. FormulaC21H12ClF5N2

别名和识别编码

Chemical Name2-(2-Chloro-4-Fluorobenzyl)-3-(4-Fluorophenyl)-7-(Trifluoromethyl)-2H-Indazole
Chemical Name Translation2-(2-氯-4-氟苄基)-3-(4-氟苯基)-7-(三氟甲基)-2H-吲唑
Chemicalbook IDCB22626329
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相关文献及参考

  • [2]. Giannarelli C, et al. Synergistic effect of liver X receptor activation and simvastatin on plaque regression and stabilization: an magnetic resonance imaging study in a model of advanced atherosclerosis. Eur Heart J. 2012 Jan;33(2):264-73.
  • [3]. Quinet EM, et al. LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse. J Lipid Res. 2009 Dec;50(12):2358-70.
  • [4]. DiBlasio-Smith EA, et al. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells. J Transl Med. 2008 Oct 16;6:59.
  • [1]. Villa GR, et al. An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers. Cancer Cell. 2016 Nov 14;30(5):683-693.
  • [1]. Villa GR, et al. An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers. Cancer Cell. 2016 Nov 14;30(5):683-693.
  • [2]. Giannarelli C, et al. Synergistic effect of liver X receptor activati

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Halogenated 卤化物 (氟氯溴碘)
  5. Fluoro 氟化物
  1. Medical Research Areas
  2. Metabolism
  3. LXR  (肝X受体)

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