Tandospirone
CAS 87760-53-0 MFCD87760530
化学结构图
SMILES: O=C1[C@@H]2[C@@H]([C@H]3C[C@@H]2CC3)C(=O)N1CCCCN1CCN(CC1)C1N=CC=CN=1 |&1:2,3,4,6|
化学属性
| Mol. Weight | 383.49 |
|---|---|
| Mol. Formula | C21H29N5O2 |
别名和识别编码
| CAS Number | 87760-53-0 |
|---|---|
| Chemical Name | Tandospirone |
| Synonym | (3aR,4S,7R,7aS)-rel- |
| Chemical Name Translation |
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
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相关文献及参考
- [2]. Xuefei Huang, et al. Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms. Oncotarget. 2017 Nov 24; 8(60): 102705–102720.
- [3]. Kyoko Nishitsuji, et al. The pharmacokinetics and pharmacodynamics of tandospirone in rats exposed to conditioned fear stress. Eur Neuropsychopharmacol. 2006 Jul;16(5):376-82.
- Evans, S.M., et al.: J. Pharmacol. Exp. Ther., 271, 683 (1994),
- Seymour, P.A., et al.: Prog. Clin. Biol. Res., 361, 453 (1990),
- [1]. Hamik A, et al. Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites. Biol Psychiatry. 1990 Jul 15;28(2):99-109.
- [1]. Hamik A, et al. Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites. Biol Psychiatry. 1990 Jul 15;28(2):99-109.
- [2]. Xuefei Huang, et al. Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of c
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