(2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol (2R,3R,4S,5R)-2-(6-(((R)-2,3-二氢-1H-茚-1-基)氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇

CAS 96392-15-3 MFCD96392153

化学结构图

96392-15-3
SMILES: OC[C@@H]1O[C@@H](C(O)[C@@H]1O)N1C=NC2C(N[C@H]3CCC4C=CC=CC=43)=NC=NC1=2 |&1:2,4,7,15|

化学属性

Mol. Weight383.4
Mol. FormulaC19H21N5O4

别名和识别编码

CAS Number96392-15-3
Chemical Name(2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol
Synonym N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine CI 947 PD 117519
Chemical Name Translation(2R,3R,4S,5R)-2-(6-(((R)-2,3-二氢-1H-茚-1-基)氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇
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分类

  • Carbohydrates & Derivatives
  • Nucleotides
  • Bases & Related Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.

相关文献及参考

  • [2]. Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42(4):709-24.
  • [3]. Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34(1):27-32.
  • Daly, J., et al.: Biochem. Pharmacol., 43, 1089 (1992),
  • [1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9.
  • [1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9.
  • [2]. Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42(4):709-24.
  • [3]. Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34(1):27-32.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adenosine Receptor  (腺苷受体)

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