1,1-Dichlorodimethyl Ether 1,1-二氯甲醚

CAS 4885-02-3 MFCD00000828

化学结构图

4885-02-3
SMILES: COC(Cl)Cl

化学属性

Mol. FormulaC2H4Cl2O
Mol. Weight115
Refractive index1.4280 to 1.4320
Boiling Point85
Density1.271
Flash Point22°C(lit.)
Appearance 无色液体。沸点85℃,溶于甲醇、乙醇、丙酮、苯。
Stability对湿度敏感

别名和识别编码

Chemical Name1,1-Dichlorodimethyl Ether
Synonym 1 1,1-DICHLORODIMETHYL ETHER 1,1-Dichlormethylether 1,1-Dichloromethyl methyl ether 1,1-二氯甲醚 1-二氯甲醚 2,2-二氯甲基甲醚 ALPHA,ALPHA-DICHLOROMETHYL METHYL ETHER ASYM-DICHLORODIMETHYL ETHER CH3OCHCl2 Dichlormethyl-methylether Dichloromethylmethyl Ether, dichloromethyl methyl Methane,dichloromethoxy- alpha,alpha-Dichloromethyl ether alpha,alpha-Dichloromethyl methyl ether alpha,alpha-dichloromethylether asym. Dichlordimethylether dichloromethoxymethane {} {} {} {} {} {} { Α,Α-二氯甲基甲醚 α,α'-dichloromethyl methyl ether α,α-Dichlorodimethyl ether α,α-二氯甲基甲醚 1,1-二氯二甲醚 α,α−Dichloromethyl methyl ether 二氯甲基甲醚
CAS Number4885-02-3
PubChem Substance ID21004
EC Number225-498-9
Beilstein Registry Number1900293
MDL NumberMFCD00000828
Reaxys-RN1900293
Chemical Name Translation1,1-二氯甲醚
InChIKeyGRTGGSXWHGKRSB-UHFFFAOYSA-N
Wiswesser Line NotationGYGO1
LabNetwork Molecule IDLN00201397
InChIInChI=1S/C2H4Cl2O/c1-5-2(3)4/h2H,1H3
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分类

  • {SNA} Building Blocks, C2 to C7, Chemical Synthesis, Ethers, Organic Building Blocks, Oxygen Compounds
  • {uni_hamburg} no charge; 1fragment
  • Building Blocks, C2 to C8, Chemical Synthesis, Ethers, Organic Building Blocks, Oxygen Compounds

产品应用

  • 有机合成中间体。

相关文献及参考

  • Short: III/31a
  • Short: II/25B
  • Beilstein: 2,IV,43

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H302 Harmful if swallowed 吞食有害
  • H302+H332
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 3 C
RTECSKN8150000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P330+P331
  • P301+P330+P331+P310
  • P303+P361+P353
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P337+P313
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 1992 2924
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R10 Flammable 易燃
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R23/24 Toxic by inhalation and in contact with skin 吸入及皮肤接触都有毒
  • R33 Danger of cumulative effects 有累积作用的危险
  • R34 Causes burns 会导致灼伤
  • R37 Irritating to respiratory system 刺激呼吸道
Packing GroupII
Hazard Class3/8
Storage condition 2-8°C 储存温度2-8℃,充氩保存
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 163,633,1969

其他信息

  • F:21
  • 下游产品:
  • 方法一:将甲酸甲酯滴加到五氯化磷和三氯氧磷的混合物中,加料温度保持10-20℃,然后在30℃搅拌反应1h。减压蒸馏,得1,1-二氯甲醚,产率77-84%。
  • MOL 文件:4885-02-3.mol
  • Acros Organics:alpha,alpha-二氯甲基甲醚 alpha,alpha-Dichloromethyl methyl ether, 97%(4885-02-3)
  • 用途一:有机合成中间体。
  • Sigma Aldrich:4885-02-3(sigmaaldrich)
  • 上游原料:三氯氧磷 --> 五氯化磷 --> 甲酸甲酯
  • TCI Shanghai:二氯甲基甲基醚 Dichloromethyl Methyl Ether,>;97.0%(GC)(4885-02-3)
  • 1,1-二氯甲醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D1645 二氯甲基甲基醚 Dichloromethyl Methyl Ether 25G 569元 2014/06/02 D1645 二氯甲基甲基醚 Dichloromethyl Methyl Ether 250G 3380元 2010/06/21 113470100 1,1-二氯甲醚 1,1-Dichlorodimethyl ether 97% 10 GR 242元

系列性分类


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