2,3-Dichloro-1-Propene 2,3-二氯-1-丙烯

CAS 78-88-6 MFCD00000943

化学结构图

78-88-6
SMILES: C=C(Cl)CCl

化学属性

Mol. FormulaC3H4Cl2
Mol. Weight111
Refractive index1.4600 to 1.4620
Vapor Density3.8 (vs air)
Boiling Point94
Vapor Pressure44 mmHg ( 20 °C)
Density1.204
Flash Point10°C(lit.)
TSCAYes
Melting Point-83°
Solubility<0.1 G/100 ML AT 22 ºC

别名和识别编码

Chemical Name2,3-Dichloro-1-Propene
Synonym 1,2-Dichloro-2-propene 1-Propene, 2,3-dichloro- 1-propene,2,3-dichloro- 2,3-DICHLORO-1-PROPENE 2,3-Dichloro-1-propene 2,3-Dichloropropylene 2,3-Dichlorpropen 2,3-二氯-1-丙烯 2-CHLOROALLYL CHLORIDE 2-Chloroallyl Chloride 2-chloro-allyl chloride 2,3-Dichloropropylene Dichloropropene, 2,3- propylene,2,3-dichloro 中文名:2,3-二氯丙烯
MDL NumberMFCD00000943
CAS Number78-88-6
PubChem Substance ID87567088
EC Number201-153-8
Beilstein Registry Number1361491
Reaxys-RN1361491
Chemical Name Translation2,3-二氯-1-丙烯
Wiswesser Line NotationG1YGU1
LabNetwork Molecule IDLN00193259
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分类

  • {Chemicalbook} 农药中间体: 除草剂中间体: 氨基甲酸酯类除草剂
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Alkenyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks

相关文献及参考

  • Short: II/25C
  • Short: III/20a
  • Electron-acceptor, with concomitant reduction to allene, in a high-yield coupling of aryl Grignard reagents to symmetrical biaryls: Tetrahedron Lett., 29, 1293 (1988):
  • Reductive elimination with Zn powder gives allene free from methylacetylene: Org. Synth. Coll., 5, 22 (1973).

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H318 Causes serious eye damage 严重伤害眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H331 Toxic if inhaled 吸入中毒
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P303+P361+
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P313
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P332+P313
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
RTECSUC8400000
Packing GroupII
UN Number 2047
Risk Statements
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R52/53
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Hazard Codes 3
Storage condition 0-10 0-10°C 2-8°C
Hazard Class3
Warnings 危化品目录(2015)
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1580 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,48,1982

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 203,81,1988

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 625 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 412,17,1998

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 100 umol/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   20,263,1983

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 225 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 266,117,1992

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 3 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 300 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Vol

Restrict 危险品

其他信息

  • 2,3-二氯丙烯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0406 2,3-二氯-1-丙烯 2,3-Dichloro-1-propene 500G 3810元 2014/06/02 D0406 2,3-二氯-1-丙烯 2,3-Dichloro-1-propene 25G 454元 2010/06/21 113695000 2,3-二氯丙烯 2,3-Dichloro-1-propene 98% 500 ML 5666元
  • 上游原料:1,2,3-三氯丙烷
  • 灭火剂:泡沫, 干粉, 二氧化碳, 砂土
  • 图谱信息:2,3-二氯丙烯(78-88-6)核磁图( 1 HNMR) 2,3-二氯丙烯(78-88-6)核磁图( 13 CNMR) 2,3-二氯丙烯(78-88-6)红外图谱(IR2) 2,3-二氯丙烯(78-88-6)红外图谱(IR3) 2,3-二氯丙烯(78-88-6)红外图谱(IR1) 2,3-二氯丙烯(78-88-6)质谱(MS)
  • 方法一:其制备方法是将36%氢氧化钠水溶液加入到反应釜中,搅拌、加热,使部分水蒸出直至碱液达到70%,在98~115℃滴加三氯丙烷,加毕回流2 h,分馏,收集92~98℃馏分,分出水分,再精馏得成品。 ClCH 2 ClCHClCH 2 +NaOH[Δ]→ClCH 2 ClC=CH 2 +NaCl+H 2 O
  • MSDS 信息:2,3-二氯丙烯(78-88-6).msds
  • 用途三:用作植物生长调节剂矮健素原料。
  • 急性毒性:口服-大鼠 LD50: 320 毫克/公斤;吸入-小鼠LC50: 3.1 克/立方米/2小时
  • Acros Organics:2,3-二氯-1-丙烯 2,3-Dichloro-1-propene, 98%(78-88-6)
  • 蒸气密度:3.8 (vs air)
  • 类别:易燃液体
  • 蒸气压:44 mm Hg ( 20 °C)
  • TCI Shanghai:2,3-二氯丙烯 2,3-Dichloro-1-propene,>;97.0%(GC)(78-88-6)
  • 海关编码:29032900
  • 刺激数据:皮肤-兔子 10 毫克/24小时 重度
  • 外观性质:无色或微黄色液体。
  • Hazard Note:Irritant/Highly Flammable
  • 可燃性危险特性:易燃; 受热分解有毒氯化物气体
  • 用途二:2,3-二氯丙烯是除草剂野燕畏的中间体。
  • Sigma Aldrich:78-88-6(sigmaaldrich)
  • 下游产品:2-氯丙烯基异硫氰酸酯 --> 四氯丙烷
  • 爆炸物危险特性:与空气混合形成爆炸性混合物;
  • 毒性分级:高毒
  • 方法二:由三氯丙烷与氢氧化钠反应而得。
  • Alfa Aesar:2,3-二氯-1-丙烯,97% 2,3-Dichloro-1-propene, 98%(78-88-6)
  • 用途一:用作植物生长调节剂矮状素的中间体
  • 储运特性:库房通风低温干燥; 与氧化剂分开储运存放
  • MOL 文件:78-88-6.mol

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