Iodoethane 碘乙烷

CAS 75-03-6 MFCD00001091

化学结构图

75-03-6
SMILES: CCI

化学属性

Mol. FormulaCH3CH2I
Mol. Weight156
Density1.95
Refractive index1.5100 to 1.5150
Vapor Density5.38 (vs air)
Boiling Point69-73
Vapor Pressure100 mmHg ( 18 °C)
Melting Point-108
Flash Point>73°(163°F)
TSCAYes
Solubility4 G/L (20 ºC)
Stability光及湿度敏感

别名和识别编码

Chemical NameIodoethane
Synonym 1-IODOETHANE 1-Iodoethane 10doethane(ethyliodide) C2H5I ETHYL IODIDE Ethane, iodo- Ethane,iodo- Ethyl iodide EthylIodideForSysnthesis Ethyliodid Ethyliodide Ethyljodid Hydriodic ether IODOETHANE IODOETHANE REAGENTPLUS(TM) 99% IODOETHANE, REAGENTPLUS, 99% Iodethan Iodoethane Jodethan Monoiodoethane ethaneiodide ethyl iodide iodo-ethan iodo-ethane iodured’ethyle Äthyljodid 乙基碘 乙基碘; 碘化乙基 乙烷基碘化物 碘乙烷 碘乙烷, 98+%, 与铜稳定 碘乙烷, 98+%, 含铜作稳 碘乙烷,乙基碘 碘化乙基
MDL NumberMFCD00001091
CAS Number75-03-6
EC Number200-833-1
Beilstein Registry Number505934
PubChem Substance ID87571463
Merck Number3813
Reaxys-RN505934
Chemical Name Translation碘乙烷
Wiswesser Line NotationI2
LabNetwork Molecule IDLN00195836
InChIInChI=1S/C2H5I/c1-2-3/h2H2,1H3
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分类

  • {uni_hamburg} no charge; 1fragment
  • {SNA} Essential Chemicals, Inorganic Salts, Solutions and Reagents, Reagent Plus, Research Essentials

产品应用

  • A useful synthetic reagent for the introduction of ethyl groups

相关文献及参考

  • Short: II/19c
  • Merck: 14,3813 Beilstein:1,96
  • Merck: 14,3813
  • Short: II/19b
  • Short: II/14a

安全信息

Signal word Danger Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R10 Flammable 易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P312
  • P301+P312+P330
  • P302+P352
  • P302+P352+P333+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P337+P313
  • P342+P311
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSKI4750000
Packing GroupIII
UN Number UN2810 1993
Storage condition Store at R.T. Light Sensitive Moisture & Light Sensitive 密封避光保存。 充氩保存
Hazard Codes
Hazard Class3
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 65 gm/m3/30M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAVUAI Fiziologicheski Aktivnye Veshchestva.  Physiologically Active
   Substances.  (Izdatel'stvo Naukova Dumka, Kiev, USSR)  No.1-    1966-
   Volume(issue)/page/year: 7,35,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 3,99,1954

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   46,277,1980

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   46,277,1980

Warnings 危化品目录(2015)
Restrict 危险品

其他信息

  • 外观性质:无色澄清重质液体,有醚的气味。
  • 用途一:用作分析试剂,也用于有机合成
  • 蒸气密度:5.38 (vs air)
  • 用途四:测定矿物折射指数,校正折光计,分离矿物,心脏血液排出量测定。用作化学试剂、医药用助渗剂(测定心血液输出量)。也用于有机合成和用作试剂。甲状腺肿治疗药,植物生长刺激素等。
  • 上游原料:红磷 --> 黄磷 --> 工业乙醇
  • 图谱信息:碘乙烷(75-03-6)核磁图( 13 CNMR) 碘乙烷(75-03-6)红外图谱(IR2) 碘乙烷(75-03-6)核磁图( 1 HNMR) 碘乙烷(75-03-6)红外图谱(IR1) 碘乙烷(75-03-6)质谱(MS)
  • MSDS 信息:碘乙烷(75-03-6).msds
  • 类别:有毒物品
  • TCI Shanghai:碘乙烷(含稳定剂铜屑) Iodoethane (stabilized with Copper chip),>;99.0%(GC)(75-03-6)
  • 灭火剂:泡沫、干粉、砂土
  • 下游产品:2-甲基-4-羧基吡啶 --> 碱性红 1 --> 2-乙氧基苯甲酸 --> 1-BOC-4-乙基-4-哌啶甲酸 --> 5-乙基-2-糠醛 --> 3-苯基环氧乙烷甲酸乙酯 --> 3-乙氧基-1,2-丙二胺 --> 非那西丁 --> 邻苯二乙醚 --> 四碘甲烷 --> 1-乙基-6,7-亚甲氧基-4-喹啉酮-3-羧酸 --> 2-乙酰基-3-乙基吡嗪 --> 加拉碘铵
  • 有醚样气味,质重,具强折光性,在空气及光线下能游离碘,使溶液成黄色至红色(加入汞粒或银箔振摇可以除去颜色),久置变红。溶于乙醇、乙醚,能与大多数有机溶剂混溶,微溶于水并逐渐分解。
  • 敏感性:Light Sensitive
  • Alfa Aesar:碘乙烷,98+%,与铜稳定 Iodoethane, 98+%, stab. with copper(75-03-6)
  • 方法一:由乙醇与三碘化磷反应而得。将工业乙醇和赤磷放入反应瓶内,在水浴上加热回流,缓缓加入碘粒。加毕,继续回流3h。然后将反应液蒸馏,蒸出黄色粗品,经洗涤,干燥而得成品。另外,由乙烯与碘化氢加成也可制取碘乙烷。
  • MOL 文件:75-03-6.mol
  • 可燃性危险特性:明火、高热可燃; 高热分解或与水、氧化剂反应生成有毒碘化物气体
  • 碘乙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80062616 碘乙烷;乙基碘 100ml 156元 2011/08/23 80062780 碘乙烷;乙基碘 25ml 138.1元 2011/04/16 I0058 碘乙烷(含稳定剂铜屑) Iodoethane (stabilized with Copper chip) 500G 1280元
  • 用途二:在有机合成中广泛用作乙基化试剂,医药工业中用作助诊剂
  • 蒸气压:100 mm Hg ( 18 °C)
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂分开存放
  • 急性毒性:腹腔- 大鼠 LD50: 330 毫克/ 公斤; 腹腔- 小鼠 LD50: 560 毫克/ 公斤
  • 毒性分级:高毒
  • F:1-8
  • Sigma Aldrich:75-03-6(sigmaaldrich)
  • 用途三:用作化学试剂、医药用助渗剂(测定心血液输出量)。也用于有机合成和用作试剂。甲状腺肿治疗药,植物生长刺激素等。
  • Acros Organics:Iodoethane, stabilized with silver, 99%(75-03-6)

系列性分类