2-Aminoanthraquinone 2-氨基蒽醌

CAS 117-79-3 MFCD00001233

化学结构图

117-79-3
SMILES: Nc1ccc2c(c1)C(=O)c1ccccc1C2=O

化学属性

Mol. FormulaC14H9NO2
Mol. Weight223.23
Melting Point292-295°C
Flash Point283°C
TSCAYes
Solubility不溶于水、醚、碱液,溶于乙醇、苯、氯仿、丙酮。
Boiling Point364.52 °C at 760 mmHg

别名和识别编码

Chemical Name2-Aminoanthraquinone
CAS Number117-79-3
PubChem Substance ID8341
EC Number204-208-4
Beilstein Registry Number14(3)429
MDL NumberMFCD00001233
Synonym 2-Aminoanthraquinone {LY} 2-Aminoanthraquinone {} {LY} 2-Aminoanthraquinone {} {} {LY} 2-Aminoanthraquinone {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Aminoanthraquinone {} {} {} {} {} {} {} {} {} {} {} {}
Reaxys-RN745903
Chemical Name Translation2-氨基蒽醌
InChIKeyXOGPDSATLSAZEK-UHFFFAOYSA-N
Wiswesser Line NotationL C666 BV IVJ EZ
LabNetwork Molecule IDLN00221355
InChIInChI=1S/C14H9NO2/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7H,15H2
Canonical SMILESO=C1C2=C(C=CC=C2)C(C3=CC=C(N)C=C13)=O
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分类

  • Building Blocks, C13 to C14, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
  • {SNA} Building Blocks, C13 to C14, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks

相关文献及参考

  • Beil. 14 ,IV,447
  • Aldrich MSDS 1 , 58:B / Corp MSDS 1 (1), 135:C / FT-IR 1 (2), 89:D / FT-IR 2 (2), 2498:D / IR-Spectra (3), 901:D / IR-Spectra (2), 788:F / RegBook 1 (2), 1691:H / Sax 6 , 190 / Structure Index 1 , 268:B:7

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xn
Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H302+H312+H332
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSCB5120000
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P308+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P312+P330
  • P302+P350
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word Warning
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Packing GroupII
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3780 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,191,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5600 gm/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,191,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 115 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-144,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1890 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 27,191,1982

{hazard

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 21(12),27,1977

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   5),1,1985

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 6 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   24,96,1994

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   5),1,1985

Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • MSDS 信息:2-氨基蒽醌(117-79-3).msds
  • Alfa Aesar:2-氨基蒽醌,tech.90% 2-Aminoanthraquinone, tech. 90%(117-79-3)
  • 2-氨基蒽醌价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0255 2-氨基蒽醌 2-Aminoanthraquinone 500G 883元 2014/06/02 A0255 2-氨基蒽醌 2-Aminoanthraquinone 25G 195元 2010/05/25 L03368 2-氨基蒽醌, tech. 90% 2-Aminoanthraquinone, tech. 90% 500g 830元
  • 毒性分级:中毒
  • 类别:有毒物品
  • 用途一:用于制蒽醌染料等
  • 上游原料:硫酸铜 --> 3-硝基苯磺酸钠 --> 2-蒽醌磺酸 --> 2-氯蒽醌 --> 防染盐S
  • 外观性质:红色或橙棕色针状结晶。
  • 图谱信息:2-氨基蒽醌(117-79-3)红外图谱(IR1) 2-氨基蒽醌(117-79-3)核磁图( 1 HNMR) 2-氨基蒽醌(117-79-3)红外图谱(IR2) 2-氨基蒽醌(117-79-3)核磁图( 13 CNMR) 2-氨基蒽醌(117-79-3)质谱(MS)
  • 急性毒性:腹腔-小鼠LD50: 1500 毫克/公斤
  • Sigma Aldrich:117-79-3(sigmaaldrich)
  • 下游产品:颜料蓝 60 --> 阳离子蓝 FGL --> 还原黄G --> 还原棕 3 --> 还原橙16 --> 溶剂蓝63 --> 还原蓝 6
  • TCI Shanghai:2-氨基蒽醌 2-Aminoanthraquinone,>;80.0%(LC)(117-79-3)
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • 储运特性:库房通风低温干燥
  • 方法一:(1)由蒽醌-2-磺酸铵盐氨化制得,工艺过程如下:将蒽醌-2-磺酸铵盐240kg、间硝基苯磺酸钠(防染盐S)70kg及25%氨水(含氨100%174kg)打浆,压入高压釜。加热至184-188℃,压力为3.73-3.92MPa(表压),保温压反应10h,反应毕,边冷却,边放氨。冷至80℃,将物料压入脱氨锅在80℃脱氨2h。升温至100℃,吸滤,用100℃热水3000L洗涤。将滤饼烘干,得2-氨基蒽醌。收率70%。(2)2-氯蒽醌和氨水在催化剂硫酸铜的悬浮物中经高温压反应,制得2-氨基蒽醌。先将2-氯蒽醌、硫酸铜、氨水打浆,充分混合压入氨化高压锅中,升温至213-215℃,于5.1-5.39MPa压力下反应5h,放压回收余氨。将反应产物压入过滤器,经过滤、水洗、干燥而得成品。产品规格:外观为红棕色粉末的工业品含量(以总氨值计)86.0%。原料消耗定额:2-氯蒽醌(96%)1150kg/t、氨水(95%)400kg/t、硫酸铜(96%)87.8kg/t。
  • 用途二:还原染料的中间体,主要用于制造还原蓝RSN,还原黄G,还原黄8G和1-氯-2-氨基蒽醌染料。此外,在造纸工业中可用作催化剂以节约烧碱。
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • MOL 文件:117-79-3.mol

系列性分类


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