Phenyl Salicylate 水杨酸苯酯

CAS 118-55-8 MFCD00002213

化学结构图

118-55-8
SMILES: OC1C=CC=CC=1C(=O)OC1C=CC=CC=1

化学属性

Mol. FormulaC13H10O3
Mol. Weight214.22
Boiling Point172-173 °C at 12 mmHg
Melting Point41-43 °C
Flash Point160°(320°F)
TSCAYes
Density1.25
Stability对光敏感
Appearance 水杨酸苯酯(118-55-8)为无色结晶粉末,具有愉快的芳香气味(冬青油气味)。密度1.250,熔点43℃,沸点173℃(1.6kPa)。 易溶于乙醚;苯和氯仿,溶于乙醇,几乎不溶于水和甘油。
Solubilitydioxane: 0.1 g/mL, clear, colorless

别名和识别编码

Chemical NamePhenyl Salicylate
Synonym Phenyl salicylate {LY} Phenyl salicylate {} {LY} Phenyl salicylate {} {} {LY} Phenyl salicylate {} {} {} {LY} Phenyl salicylate {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenyl salicylate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pheny
MDL NumberMFCD00002213
CAS Number118-55-8
EC Number204-259-2
Beilstein Registry Number393969
PubChem Substance ID8361
Merck Number7310
Reaxys-RN393969
Chemical Name Translation水杨酸苯酯
Wiswesser Line NotationQR BVOR
LabNetwork Molecule IDLN00193122
InChIInChI=1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
Canonical SMILESO=C(OC1=CC=CC=C1)C2=CC=CC=C2O
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分类

  • {SNA} Alphabetical Listings, Flavors and Fragrances, O-P
  • {uni
  • {SNA} Building Blocks, C12 to C63, Carbonyl Compounds, Chemical Synthesis, Esters,
  • {SNA} Building Blocks, C12 to C63, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
  • {SNA} Building Blocks,

产品应用

  • 有机合成。比色法测定铁离子。塑料的光吸收剂,防止变色。乙烯基塑料的稳定剂。定香剂。

相关文献及参考

  • Merck: 14,7310
  • Short: II/27B
  • Merck: 14,7310 Beilstein:10,76
  • Short: II/27C

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSVO6125000
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {}
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 6,149,1954

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   RMSRA6 Revue Medicale de la Suisse Romande.  (Societe Medicale de La Suisse
   Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland)  V.1-    1881-
   Volume(issue)/page/year: 15,561,1895

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 14,837,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   OCMJAJ Osaka City Medical Journal.  (Osaka City Medical Center, 1-4-54,
   Asahi-machi, Abeno-ku, Osaka 545, Japan)  V.1-    1954-
   Volume(issue)/page/year: 12,23,1966

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   OCMJAJ Osaka City Medical Journal.  (Osaka City Medical Center, 1-4-54,
   Asahi-machi, Abeno-ku, Osaka 545, Japan)  V.1-    1954-
   Volume(issue)/page/year: 12,23,1966

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1200 mg/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   OCMJAJ Osaka City Medical Journal.  (Osaka City Medical Center, 1-4-54,
   Asahi-machi, Abeno-ku, Osaka 545, Japan)  V.1-    1954-
   Volume(issue)/page/year: 12,23,1966

其他信息

  • 用途三:本品为一种紫外线吸收剂,用于塑料制品。但吸收波长范围较窄,光稳定性较差。也用作医药消毒防腐剂和用于有机合成。还用来制香料。
  • 下游产品:占吨酮 --> 水杨酰苯胺 --> 柳胺酚
  • 微有芳香气味,溶于丙酮、氯仿、乙醚和油类,极微溶于甘油。低毒,有刺激性
  • 上游原料:水杨酸 --> 酯化液
  • Acros Organics:水杨酸苯酯 Phenyl salicylate, 99%(118-55-8)
  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) 水杨酸苯酯 食品 食品用香料 用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
  • Alfa Aesar:水杨酸苯酯,99% Phenyl salicylate, 99%(118-55-8)
  • 用途四:有机合成。比色法测定铁离子。塑料的光吸收剂,防止变色。乙烯基塑料的稳定剂。定香剂。
  • MOL 文件:118-55-8.mol
  • 用途一:用作防腐剂,也用于制药、有机合成工业
  • MSDS 信息:Disperse Dye Blue EXSF(118-55-8).msds
  • 用途二:用作塑料制品的紫外线吸收剂、增塑剂、防腐剂,用于药物合成、配制香精等
  • FEMA:3960
  • 方法一:水杨酸与苯酚在催化剂硫酸存在下进行酯化。酯化液经中和、水洗、蒸馏得成品。原料消耗定额:水杨酸850kg/t、苯酚850kg/t。
  • 水杨酸苯酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30145927 水杨酸苯酯;2-羟基苯甲酸苯酯; 萨罗 250g 48元 2011/04/16 S0017 水杨酸苯酯 Phenyl Salicylate 500G 560元 2011/04/16 S0017 水杨酸苯酯 Phenyl Salicylate 25G 148元
  • 图谱信息:水杨酸苯酯(118-55-8)红外图谱(IR2) 水杨酸苯酯(118-55-8)红外图谱(IR1) 水杨酸苯酯(118-55-8)质谱(MS) 水杨酸苯酯(118-55-8)Raman光谱 水杨酸苯酯(118-55-8)核磁图( 1 HNMR) 水杨酸苯酯(118-55-8)核磁图( 13 CNMR) 水杨酸苯酯(118-55-8)红外图谱(IR3)
  • TCI Shanghai:水杨酸苯酯 Phenyl Salicylate,>;98.0%(GC)(118-55-8)
  • Sigma Aldrich:118-55-8(sigmaaldrich)

系列性分类


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