2,2-Bis(Hydroxymethyl)-2,2,2-Nitrilotriethanol 二(2-羟乙基)亚氨-三羟甲基丙烷

CAS 6976-37-0 MFCD00002853

化学结构图

6976-37-0
SMILES: OCCN(CCO)C(CO)(CO)CO

化学属性

Mol. FormulaC8H19NO5
Mol. Weight209.24
Melting Point104 °C
TSCAYes
Density1.346
SolubilitySoluble in water (~209.2 g/l) at 20 °C, and alcohol.
Boiling Point466.2±40.0 °C at 760 mmHg

别名和识别编码

Chemical Name2,2-Bis(Hydroxymethyl)-2,2,2-Nitrilotriethanol
Synonym Bis-Tris {LY} Bis-Tris {} {LY} Bis-Tris {} {} {LY} Bis-Tris {} {} {} {LY} Bis-Tris {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Bis-Tris {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number6976-37-0
PubChem Substance ID81462
EC Number230-237-7
Beilstein Registry Number2205275
MDL NumberMFCD00002853
Reaxys-RN2205275
Chemical Name Translation二(2-羟乙基)亚氨-三羟甲基丙烷
LabNetwork Molecule IDLN00192543
InChIInChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
Canonical SMILESOCC(CO)(N(CCO)CCO)CO
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分类

  • {SNA} Biochemicals and Reagents, Biological Buffers,
  • {SNA} Good’s Buffers, PharmaGrade Buffers, 生化试剂, 生物缓冲液
  • {SNA} BioXtra Buffers, Buffers A to Z, Good’s Buffers, 生化试剂, 生物缓冲液
  • {SNA} BioPerformance Certified Buffers,
  • {SNA} BioXtra Buffers, Biochemicals and Reagents, Biological Buffers, Buffers A to Z, Good’s Buffers
  • {SNA} Alphabetical, BioUltra Buffers, 生化试剂, 生物缓冲液
  • {SNA} BioPerformance Certified Buffers, Buffers / Buffer Salts, Buffers / Buffer salts, Buffers A to Z, Core Bioreagents, Good’s Buffers, Life Science Reagents for DNA/RNA Electrophoresis, Life Science Reagen

产品应用

  • 缓冲液，用于检测肌酸肌酶；也用于在冷冻干燥中有效保护血红蛋白；阴极电解液，用在IEF/2-D凝胶电泳。

相关文献及参考

  • Buffer: pH range 5.5 - 8.0.

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xn Xi Xi,Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Signal word Warning
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at r

其他信息

  • 溶于水、乙醇以及有机溶剂。
  • 图谱信息:双(2-羟乙基)氨基(三羟甲基)甲烷(6976-37-0)红外图谱(IR2) 双(2-羟乙基)氨基(三羟甲基)甲烷(6976-37-0)质谱(MS) 双(2-羟乙基)氨基(三羟甲基)甲烷(6976-37-0)Raman光谱 双(2-羟乙基)氨基(三羟甲基)甲烷(6976-37-0)红外图谱(IR1)
  • Acros Organics:双(2-羟乙基)胺三(羟甲基)甲烷/BIS-TRIS 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol, for biochemistry, 99+%(6976-37-0)
  • 海关编码:29221980
  • 敏感性:Air Sensitive
  • Alfa Aesar:2,2-双(羟基甲基)-2,2',2''-次氮基三乙醇,98+% 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol, 98+%(6976-37-0)
  • 检测方法:MP,NMR
  • BIS-Tris is an inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature. Suitable for fractionation of hemoglobin. The useful pH range for the buffer is 5.8-7.2. Has a pKa of 6.5 at 25°C.
  • F:10-23
  • MSDS 信息:2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol(6976-37-0).msds
  • 用途一:缓冲液，用于检测肌酸肌酶；也用于在冷冻干燥中有效保护血红蛋白；阴极电解液，用在IEF/2-D凝胶电泳。
  • Sigma Aldrich:6976-37-0(sigmaaldrich)
  • 外观性质:白色结晶粉末，溶于水、乙醇以及有机溶剂。熔点：103-104℃pH range 5.8 - 7.2 pKa (25 °C) 6.5
  • TCI Shanghai:双(2-羟乙基)氨基三(羟甲基)甲烷[生物研究用Good's缓冲液中的成分] Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research],>;99.0%(LC)(T)(6976-37-0)
  • 双(2-羟乙基)氨基(三羟甲基)甲烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B1493 双(2-羟乙基)氨基三(羟甲基)甲烷[生物研究用Good's缓冲液中的成分] Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research] 250G 2060元 2014/06/02 B1493 双(2-羟乙基)氨基三(羟甲基)甲烷[生物研究用Good's缓冲液中的成分] Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research] 25G 325元 2010/06/21 168875000 双(2-羟乙基)氨基(三羟甲基)甲烷 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol 99+% 500 GR 3363元
  • MOL 文件:6976-37-0.mol
  • 存储注意事项:空气敏感

系列性分类

  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. Buffers A to Z - Biological Buffers
  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. BioUltra Buffers - Biological Buffers
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for DNA/RNA Electrophoresis - Core Bioreagents
  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. BioUltra Buffers - Biological Buffers
  4. Alphabetical - BioUltra Buffers
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for DNA/RNA Electrophoresis - Core Bioreagents
  4. Buffers / Buffer salts - Life Science Reagents for DNA/RNA Electrophoresis

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