2-(2-Methoxyethoxy)ethanol 二乙二醇甲醚

CAS 111-77-3 MFCD00002871

化学结构图

111-77-3
SMILES: COCCOCCO

化学属性

Mol. FormulaC5H12O3
Mol. Weight120.15
Density1.023
Refractive index1.4240 to 1.4270
Flash Point83.89°C
TSCAYes
Boiling Point194°C at 760 mmHg
Melting Point-70°C
Autoignition Point221 °C
Vapor Density4.14 (vs air)
Vapor Pressure0.2 mmHg ( 20 °C)
Solubility溶于水、氯仿、乙醇和乙醚、可混溶于醇、酮、烃类。
Stability易吸潮

别名和识别编码

Chemical Name2-(2-Methoxyethoxy)ethanol
MDL NumberMFCD00002871
CAS Number111-77-3
Synonym Methyl-PEG2-alcohol {LY} Methyl-PEG2-alcohol {} {LY} Methyl-PEG2-alcohol {} {} {LY} Methyl-PEG2-alcohol {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methyl-PEG2-alcohol {} {} {} {} {} {} {} {} {} {} {} {}
EC Number203-906-6
Merck Number6037
Beilstein Registry Number1697812
Reaxys-RN1697812
PubChem Substance ID87572573
Chemical Name Translation二乙二醇甲醚
Wiswesser Line NotationQ2O2O1
LabNetwork Molecule IDLN00195651
Canonical SMILESCOCCOCCO
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分类

  • {uni_hamburg} no charge; alcohol; ether; 1fragment

产品应用

  • 溶剂。有机合成中间体.

相关文献及参考

  • Merck:14,6037
  • Short: IV/10A
  • Merck:14,6037 Beilstein:1(4)2392
  • Short: III/38A
  • Short: III/38B

安全信息

RTECSKL6125000
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY
GHS Symbol
WGK Germany1
Hazard statements
  • H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
  • H303+H313
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P304+P340+P312
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P308+P313
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P405 Store locked up. 上锁保管。
  • P304+P340
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P403+P233
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Signal word
Hazard Codes Xn
Packing GroupIII
UN Number
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2722 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GNAMAP Gigiena Naselennykh Mest.  Hygiene in Populated Places. (Izdatel'stvo
   Zdorov'ya, Kiev, USSR) V.7-    19

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2611 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GNAMAP Gigiena Naselennykh Mest.  Hygiene in Populated Places. (Izdatel'stvo
   Zdorov'ya, Kiev, USSR) V.7-    1967- Volume(issue)/page/year: 29,37,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Former

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 uL/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Gastrointestinal - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0516797

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 21650 mg/kg
SEX/DURATION            : female 7-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   6,430,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 19800 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 24,228,1993

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 3250 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.

其他信息

  • 外观性质:具有微芳香气味并略有苦味的无色液体。
  • 下游产品:二乙二醇二甲醚 --> 1-(3-三氟甲基苯基)哌嗪 --> 1-(3,5-二氯苯基)哌嗪 --> 1-(3-氟苯基)哌嗪 --> 1-(3,4-二氯苯基)哌嗪 --> 1-(4-甲氧基苯基)哌嗪 --> 1-(4-甲氧基苯基)哌嗪盐酸盐 --> 4-吗琳基-2-乙基哌嗪 --> 1-(3-(甲基苯基)哌啶 --> 1-(3-甲氧基苯基)哌嗪 --> 1-(4-甲基苯基)哌嗪 --> 1-(4-氯苯基)哌嗪 --> 1-(2-甲基苯基)哌嗪 --> 汽车制动液 --> 分散红 E-RLN
  • 用途二:用作硝化纤维素、树脂、木材着色用染料、油墨、醇醚性染料的溶剂,还用作萃取剂、改进剂等
  • 用途四:用作油墨、染料、树脂、纤维素及涂料的高沸点溶剂,也用于有机合成。该品对鼠口服LD50为9200mg/kg。
  • 毒性分级:低毒
  • 急性毒性:口服- 大鼠 LD50: 5500 毫克/ 公斤; 口服- 小鼠 LD50
  • 图谱信息:二乙二醇单甲醚(111-77-3)红外图谱(IR2) 二乙二醇单甲醚(111-77-3)质谱(MS) 二乙二醇单甲醚(111-77-3)核磁图( 13 CNMR) 二乙二醇单甲醚(111-77-3)红外图谱(IR1) 二乙二醇单甲醚(111-77-3)核磁图( 1 HNMR) 二乙二醇单甲醚(111-77-3)Raman光谱
  • TCI Shanghai:二乙二醇单甲醚 Diethylene Glycol Monomethyl Ether,>;99.0%(GC)(111-77-3)
  • 蒸气密度:4.14 (vs air)
  • 灭火剂:泡沫、干粉、二氧化碳
  • Sigma Aldrich:111-77-3(sigmaaldrich)
  • MOL 文件:111-77-3.mol
  • 二乙二醇单甲醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30059428 二乙二醇单甲醚 500ml 70元 2011/04/16 M0537 二乙二醇单甲醚 Diethylene Glycol Monomethyl Ether 25ML 150元 2011/04/16 M0537 二乙二醇单甲醚 Diethylene Glycol Monomethyl Ether 500ML 230元
  • 可燃性危险特性:遇明火、高温、强氧化剂可燃; 燃烧排放刺激烟雾
  • Alfa Aesar:二乙二醇单甲醚,98% Diethylene glycol monomethyl ether, 98%(111-77-3)
  • 海关编码:29094200
  • 敏感性:Hygroscopic
  • 上游原料:乙醇 --> 甲醇 --> 正丁醇 --> 曙光红(四溴荧光素) --> 乙二醇甲醚
  • 用途三:用作溶剂及制备酯类衍生物的中间体
  • 类别:可燃物品
  • 蒸气压:0.2 mm Hg ( 20 °C)
  • MSDS 信息:二乙二醇单甲基醚(111-77-3).msds
  • 用途一:用作硝化纤维素、树脂、木材着色用染料、油墨、醇醚性染料的溶剂,还用作萃取剂、改进剂和中间体
  • 用途五:溶剂。有机合成中间体.
  • Acros Organics:2-(2-甲氧基乙氧基)乙醇/甲基卡必醇 2-(2-Methoxyethoxy)ethanol, 99%(111-77-3)
  • 有芳香气味。有吸湿性。能与水、乙醇、甘油、乙醚、丙酮、二甲基乙酰胺等混溶。半数致死量(大鼠,经口)9.21g/kg。有刺激性。
  • 储运特性:包装完整、轻装轻卸; 库房通风、远离明火、高温、与氧化剂分开存放
  • 方法一:由乙二醇单甲醚与环氧乙烷反应而得。
  • 刺激数据:眼- 兔子 500 毫克/ 24小时 轻度

系列性分类