Phenidone 菲尼酮

CAS 92-43-3 MFCD00003094

化学结构图

92-43-3
SMILES: O=C1CCN(c2ccccc2)N1

化学属性

Mol. FormulaC9H10N2O
Mol. Weight162.19
Melting Point119-121°C
TSCAYes
Solubility溶于热水
Density1.188
Boiling Point288.88 °C at 760 mmHg

别名和识别编码

Chemical NamePhenidone
CAS Number92-43-3
Alfabeta NamePHENYLPYRAZOLIDINONE 13---
MDL NumberMFCD00003094
Synonym Phenidone {LY} Phenidone {} {LY} Phenidone {} {} {LY} Phenidone {} {} {} {LY} Phenidone {} {} {} {} {LY} Phenidone {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID87574404
EC Number202-155-1
Beilstein Registry Number131856
Merck Number7309
Reaxys-RN131856
Chemical Name Translation菲尼酮
Wiswesser Line NotationT5NMVTJ AR
LabNetwork Molecule IDLN00162246
Canonical SMILESO=C1NN(C2=CC=CC=C2)CC1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Cell Biology, Chemical Synthesis, Heterocyclic Building Blocks, P, Pyrazoles
  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, PA-PH, Pyrazoles, 细胞生物学
  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, P, Pyrazoles, 细胞生物学
  • {SNA} Building Blocks, C9, Chemical Synthesis,

产品应用

  • 感光材料显影剂。

相关文献及参考

  • [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58.
  • [3]. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587.
  • Merck: 14,7309
  • Merck: 14,7309 Beilstein:24,2
  • Short: EINECS
  • Short: IV/20C
  • [1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210.
  • [1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210.
  • [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive ag

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany2
Hazard statements
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSUQ8750000
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310+P330
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Packing GroupIII
UN Number 2811 UN 2811 6.1/PG 3
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R51/53
Hazard Codes 6.1 Xn,N Xn;N
Hazard Class6.1 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(1),49,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
RO

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1310 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(9)

Storage condition 2-8°C, sealed storage, away from moisture and light {LY} 2-8°C, sealed storage, away from moisture and light {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

其他信息

  • 菲尼酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30145725 1-苯基-3-吡唑烷酮 50g 22元 2011/04/16 P0153 1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone 500G 1990元 2011/04/16 P0153 1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone 25G 233元
  • 图谱信息:菲尼酮(92-43-3)核磁图( 1 HNMR) 菲尼酮(92-43-3)核磁图( 13 CNMR) 菲尼酮(92-43-3)红外图谱(IR2) 菲尼酮(92-43-3)质谱(MS) 菲尼酮(92-43-3)红外图谱(IR3) 菲尼酮(92-43-3)红外图谱(IR1)
  • 溶于热水，极溶于稀酸和碱，溶于沸苯和醇，实际上不溶于醚和石油醚。
  • 用途二:感光材料显影剂。
  • MSDS 信息:1-Phenyl-3-pyrazolidinone(92-43-3).msds
  • 用途一:用作照相显影剂
  • MOL 文件:92-43-3.mol
  • Sigma Aldrich:92-43-3(sigmaaldrich)
  • TCI Shanghai:1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone,>;98.0%(T)(92-43-3)
  • 上游原料:甲醇钠 --> 苯肼
  • Alfa Aesar:1-苯基-3-吡唑酮,97% 1-Phenyl-3-pyrazolidinone, 97%(92-43-3)
  • 外观性质:近似白色结晶。溶于热水，极溶于稀酸和碱，溶于沸苯和醇，实际上不溶于醚和石油醚。熔点：119-123 °C
  • 海关编码:29331990
  • Acros Organics:1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidinone, 97%(92-43-3)

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. P - Bioactive Small Molecules
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrazines 吡嗪
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrazoles 吡唑
  5. C9 - Pyrazoles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyrazoles 吡唑
  1. Medical Research Areas
  2. Metabolism
  3. Lipoxygenase  (脂氧合酶)

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