Phenol red 酚红

CAS 143-74-8 MFCD00003552

化学结构图

143-74-8
SMILES: [O-]S1([O-])OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

化学属性

Mol. FormulaC19H14O5S
Mol. Weight354.38
TSCAYes
Boiling Point>300 °C at 760 mmHg
Melting Point>300 °C
SolubilityPractically insoluble in chloroform, ether. Soluble in aqueous alkali hydroxides or carbonates with red color (removed by boiling with zinc dust). Solubility in water: approximately 1g/1300ml. Solubility in alcohol: approximately 1g/350ml
Density1.477
Flash Point>300°C
Appearance 深红色结晶性粉末。1g本品溶于1300ml水，约350ml醇，500ml丙酮，几乎不溶于醚和氯仿，溶于氢氧化碱或碳酸碱溶液中呈深红色，在空气中稳定。

别名和识别编码

Chemical NamePhenol red
MDL NumberMFCD00003552
PubChem Substance ID87574854
CAS Number143-74-8
Reaxys-RN326470
Beilstein Registry Number19(3/4)1128
Merck Number7247
Synonym Phenol Red {LY} Phenol Red {} {LY} Phenol Red {} {} {LY} Phenol Red {} {} {} {LY} Phenol Red {} {} {} {} {LY} Phenol Red {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} { {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenol Red {} {} {} {} {} {} {} {} {} {} {}
EC Number205-609-7
Chemical Name Translation酚红
Wiswesser Line NotationT56 BSWO DHJ DR DQ& DR DQ
LabNetwork Molecule IDLN00194920
InChIInChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
Canonical SMILESO=S1(OC(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)C4=CC=CC=C41)=O
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分类

  • {SNA} Indicators, Titration,
  • In Vivo/In Vitro Tracking of Stem Cells, Assays and Reagents for Measuring Cytotoxicity, Proliferation and Viability, Cell Biology, Cell Culture, Cell Culture Supplies, Cell Staining for Scale-Up Cell Culture, Core Bioreagents, General Stains/Dyes for Stem Cell Biology, General Stem Cell Biology, Hematology and Histology, Labware, Life Science Reagents for Cell Culture, P, Reagents and Supplements, Research Essentials, Scale-Up Cell Culture using Corning Roller Bottles, Stains & Dyes, Stains & Dyes, A to Z, Stains and Dyes, Stains, Dyes and Indicators, Stem Cell Biology, Stem Cell Characterization
  • {SNA} In

产品应用

  • 酸碱指示剂，变色范围pH:6.8（黄）-8.4（红）。血液二氧化碳全量测定，细菌血清检验中制备双糖铁尿素培养基的指示剂。其钠盐用于测定肝功能。

相关文献及参考

  • Merck: 14,7247 Beilstein: 19,V,3,457
  • Merck: 14,7247
  • Acid-base indicator: approx pH 6.8 - 8.2.

安全信息

WGK Germany3
Signal word
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSSJ7490000
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
GHS Symbol
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition RT, protect from light {LY} RT, protect from light Store at RT. {} {LY} RT, protect from light {} {} {LY} RT, protect from light {} {} {} {LY} RT, protect from light {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 4(2),185,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1368 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,930,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 752 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,930,1990

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   AEMIDF Applied and Environmental Microbiology.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.31-    1976-
   Volume(issue)/page/year: 42,641,1981

其他信息

  • MSDS 信息:Phenolsulfonephthalein(143-74-8).msds
  • 酚红价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 71032460 酚红;苯酚磺酰酞; 苯酚磺酞; 苯酚红 25g 30元 2011/04/16 P0101 酚红(0.04%的水溶液)[用于pH值检测] Phenol Red (0.04% in Water) [for pH Determination] 500ML 377元 2011/04/16 P0100 酚红 Phenol Red 25G 426元
  • 下游产品:溴酚蓝
  • 用途二:酸碱指示剂，变色范围pH:6.8（黄）-8.4（红）。血液二氧化碳全量测定，细菌血清检验中制备双糖铁尿素培养基的指示剂。其钠盐用于测定肝功能。
  • 用途一:用作酸碱指标剂，变色范围pH:6.8（磺）-8.4（红）。也用于生化研究。
  • Acros Organics:苯酚红/酚红 分析级别 Phenol Red, conform to ACS, pure(143-74-8)
  • 方法一:将邻磺基苯甲酸酐与苯酚共热熔化，加入无水氯化锌于135-140℃反应7h，然后将缩合物倒入热水中，用滤，用水洗涤固体，进一步用酸碱沉淀法提纯而得成品。
  • 图谱信息:酚红(143-74-8)质谱(MS) 酚红(143-74-8)红外图谱(IR1) 酚红(143-74-8)红外图谱(IR2)
  • Alfa Aesar:苯酚红,ACS Phenol Red, ACS(143-74-8)
  • 上游原料:氯化锌 --> 2-磺基苯甲酸酐
  • TCI Shanghai:酚红(0.1%的乙醇(约20%)溶液)[用于滴定] Phenol Red (0.1% in ca. 20% Ethanol) [for Titration](143-74-8)
  • MOL 文件:143-74-8.mol
  • 1g本品溶于1300ml水，约350ml醇，500ml丙酮，几乎不溶于醚和氯仿，溶于氢氧化碱或碳酸碱溶液中呈深红色，在空气中稳定。
  • 海关编码:29349990
  • Sigma Aldrich:143-74-8(sigmaaldrich)

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Titration - Analytical Reagents
  4. Indicators - Titration
  5. pH Indicators - Solids - Indicators
  1. Life Science 生命科学
  2. Cell Culture 细胞培养
  3. Reagents and Supplements - Cell Culture
  4. Assays and Reagents for Measuring Cytotoxicity, Proliferation and Viability - Reagents and Supplements
  5. Stains, Dyes and Indicators - Assays and Reagents for Measuring Cytotoxicity, Proliferation and Viability
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Stem Cell Biology - Cell Biology
  4. General Stem Cell Biology - Stem Cell Biology
  5. Stem Cell Characterization - General Stem Cell Biology
  6. General Stains/Dyes for Stem Cell Biology - Stem Cell Characterization
  1. Analytical & Chromatography 分析化学与色谱
  2. Titration
  3. Indicators
  4. Metal Titration Indicators
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Viability and Proliferation
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Culture
  4. Cell Viability and Proliferation
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Reagents and Supplements
  4. Cell Viability and Proliferation
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Culture
  4. Reagents and Supplements
  5. Cell Viability and Proliferation