N-Methylcyclohexylamine N-甲基环己胺

CAS 100-60-7 MFCD00003832

化学结构图

100-60-7
SMILES: CNc1ccccc1

化学属性

Mol. FormulaC7H15N
Mol. Weight113
Density0.868
Refractive index1.4550 to 1.4580
Flash Point29°C(lit.)
TSCAYes
Boiling Point149
Melting Point-9 - -7
Vapor Density4 (vs air)
Vapor Pressure11 mmHg ( 40 °C)
Solubility5.4 G/100 ML (20 ºC)
Stability对空气敏感
Appearance 无色透明液体。 与多种有机溶剂混溶,微溶于水。

别名和识别编码

Chemical NameN-Methylcyclohexylamine
CAS Number100-60-7
EC Number202-869-3
Beilstein Registry Number1523664
MDL NumberMFCD00003832
Synonym Cyclohexanamine, N-methyl- Cyclohexanamine,N-methyl- Cyclohexylamine, N-methyl- METHYLAMINOCYCLOHEXANE Methylcyclohexylamine N-CYCLOHEXYLMETHYLAMINE N-Cyclohexyl-N-methylamine N-Cyclohexylmethylamine N-METHYLCYCLOHEXYLAMINE N-Methyl-N-cyclohexylamine N-Methylcyclohexanamine N-Methylcyclohexylamine N-methyl-Cyclohexanamine N-环己基甲胺 N-环己基甲胺; N-环己基甲胺;N-甲环己胺 N-甲基环己胺 N-甲環己胺 cyclohexyl(methyl)amine cyclohexyl-methyl-amine methyla methylcyclohexylamine,[corrosivelabel] methylcyclohexylamine,[flammableliquidandcorrosivelabels] methylcyclohexylamine,[flammableliquidlabel] n-methyl-cyclohexanamin n-methyl-cyclohexylamin
PubChem Substance ID87572293
Chemical Name TranslationN-甲基环己胺
Reaxys-RN1523664
LabNetwork Molecule IDLN00221427
InChIInChI=1S/C7H15N/c1-8-7-5-3-2-4-6-7/h7-8H,2-6H2,1H3
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分类

  • {uni_hamburg} no charge; carbocycle; alicycle; 6RingOnly; 6ring; 1fragment
  • {SNA} Amines, Building Blocks, C7, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

相关文献及参考

  • Short: III/38B Title: Refractive Indices of Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38B Year: 1996 Keyword: organic compounds; refractive index; liquids ISBN: 3-540-60596-7 ISBN: 978-3-540-60596-6 Internet Resource: DOI:10.1007/b85533 RefComment: VII, 4210 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices of inorganic and organic liquids and their wavelength dependence (dispension). Part A contains the inorganic, organometallic, and organononmetallic liquids, and the binary liquid mixtures (about 900 pure substances and their mixtures). Part B contains data of more than 7600 organic liquids.
  • Short: IV/18A Title: Viscosity of Pure Organic Liquids and Binary Liquid Mixtures: Pure Organometallic and Organononmetallic Liquids, Binary Liquid Mixtures Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: IV/18A Year: 2001 Keyword: organic compounds; viscosity; liquids; mixtures ISBN: 3-540-64584-5 ISBN: 978-3-540-64584-9 Internet Resource: DOI:10.1007/b68239 RefComment: VII, 409 pages.
  • Short: IV/18B Title: Viscosity of Pure Organic Liquids and Binary Liquid Mixtures: Pure Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: IV/18B Year: 2001 Keyword: organic compounds; viscosity; liquids; mixtures Internet Resource: DOI:10.1007/b68240 RefComment: VII, 409 pages.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

Signal word Danger
GHS Symbol
WGK Germany1
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R10 Flammable 易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
  • R34 Causes burns 会导致灼伤
  • R35 Causes severe burns 会导致严重灼伤
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331+P310
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P370+P378
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSGX1529000
Packing GroupII
UN Number 2734 UN 2734 8/PG 2
Storage condition Flammables area 充氩保存 Air Sensitive
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H302 Harmful if swallowed 吞食有害
  • H302+H312
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H331 Toxic if inhaled 吸入中毒
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 8 C
Hazard Class8/3
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Skin and Appendages - corrosive (after topical exposure)
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,388,1969

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 7000 mg/m3/1H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,388,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,388,1969

其他信息

  • TCI Shanghai:N-甲基环己胺 N-Methylcyclohexylamine,>;99.0%(T)(100-60-7)
  • 下游产品:盐酸溴己新
  • 上游原料:环己酮 --> 铝 --> 环己胺 --> 氯化汞
  • Sigma Aldrich:100-60-7(sigmaaldrich)
  • 敏感性:Air Sensitive
  • 蒸气密度:4 (vs air)
  • 用途一:用作医药及染料的中间体
  • 蒸气压:11 mm Hg ( 40 °C)
  • 用途二:药物及染料中间体。用作药物盐酸溴已胺的中间体。
  • Hazard Note:Corrosive
  • 方法一:1.以环己胺为原料制得。2.由环己酮与甲胺反应而得。将铝片浸泡在甲醇中,再加氯化高汞,继续浸泡2h,升温不超过55℃,除去浸泡液。向上述活化好的铝片加乙醇,在搅拌下滴加甲胺、环己酮的混合液,加热回流,放置过夜。加入10%氢氧化钠溶液碱化,用苯提取两次,经水洗后进行蒸馏,回收苯后即馏出N-甲基环己胺。收率约80%。
  • MSDS 信息:N-Cyclohexylmethylamine(100-60-7).msds
  • 海关编码:29213099
  • Acros Organics:N-甲基环己胺 N-Methylcyclohexylamine, 98%(100-60-7)
  • MOL 文件:100-60-7.mol
  • N-甲基环己胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0202 N-甲基环己胺 N-Methylcyclohexylamine 500G 953元 2014/06/02 M0202 N-甲基环己胺 N-Methylcyclohexylamine 25G 196元 2010/06/21 146990050 N-甲基环己胺 N-Methylcyclohexylamine 98% 5 ML 278元
  • 图谱信息:N-甲基环己胺(100-60-7)核磁图( 1 HNMR) N-甲基环己胺(100-60-7)质谱(MS) N-甲基环己胺(100-60-7)核磁图( 13 CNMR) N-甲基环己胺(100-60-7)红外图谱(IR1)
  • Alfa Aesar:N-甲基环己胺,98% N-Methylcyclohexylamine, 98%(100-60-7)

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