Dansyl Chloride 丹磺酰氯

CAS 605-65-2 MFCD00003985

化学结构图

605-65-2
SMILES: CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12

化学属性

Mol. FormulaC12H12ClNO2S
Mol. Weight269.75
Melting Point70-73°C
Density1.422
TSCAYes
Solubilityacetone: 50 mg/mL
Appearance powder and chunks
Stability对湿度敏感
Boiling Point371.3°C at 760 mmHg
Flash Point178.4°C

别名和识别编码

Chemical NameDansyl Chloride
CAS Number605-65-2
Synonym Dansyl chloride {LY} Dansyl chloride {} {LY} Dansyl chloride {} {} {LY} Dansyl chloride {} {} {} {LY} Dansyl chloride {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dansyl chloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}
PubChem Substance ID11801
EC Number210-092-6
Beilstein Registry Number2217205
MDL NumberMFCD00003985
Reaxys-RN2217205
Merck Number2814
Chemical Name Translation丹磺酰氯
Wiswesser Line NotationL66J BSWG GN1&1
LabNetwork Molecule IDLN00193809
InChIInChI=1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
Canonical SMILESO=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(Cl)=O
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分类

  • {SNA} Amino Acid Analysis, Detection Products for Amino Acid Analysis, Peptide Analysis and Characterization, Peptides, 生化试剂
  • Alphabetical, Amino Acid Analysis, Amino Acids, Analytical Reagents, Analytical/Chromatography, Application Specific Reagents, Biochemicals and Reagents, Biogenic Amines, Carbohydrate Labels, Carbohydrate Labels for Chromatography, Derivatization Reagents, Derivatization Reagents HPLC, Derivatization Reagents TLC, Detection, Detection Products for Amino Acid Analysis, Fluorescence, Fluorescent Indicators and Probes, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains,
  • {SNA} Alphabetical,

产品应用

  • A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

相关文献及参考

  • Grego, B., and Hearn, M.T., High-performance liquid chromatography of amino acids, peptides and proteins. J. Chromatogr. 255 , 67-77, (1983)
  • Reagent for the preparation of fluorescent derivatives of amino acids and proteins: Biochemistry, 9, 3878 (1970); Anal. Biochem., 53, 132 (1973); 66, 104 (1975).
  • Marks, R., et al.: Br. J. Dermatol., 111, 265 (1984),
  • Kinoshita, T., et al.: Anal. Biochem., 66,104 (1975),
  • Weber, G., et al.: Biochem. J., et al.: 51, 155 (1952),

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 8 C
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSQK3688000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R34 Causes burns 会导致灼伤
UN Number 3261 UN 3261 8/PG 2
Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen 2-8°C, stored under nitrogen Moisture Sensitive {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {}
Packing GroupII
Hazard Class8
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00262

其他信息

  • Alfa Aesar:丹酰氯,97+% Dansyl chloride, 97+%(605-65-2)
  • Sigma Aldrich:605-65-2(sigmaaldrich)
  • 存储注意事项:湿度敏感;氮气保护
  • MOL 文件:605-65-2.mol
  • 图谱信息:丹酰氯(605-65-2)红外图谱(IR1)
  • Acros Organics:丹磺酰氯/二甲胺基萘磺酰氯 Dansyl chloride, 98%(605-65-2)
  • Dansyl chloride (DNSC), a primary amine reactive agent, is widely used as a fluorogenic reagent for N-terminal derivatization of amino acids and peptides and for polyamine detection by reverse phase HPLC and other analytical procedures.
  • 海关编码:29214980
  • color:yellow to orange
  • 丹酰氯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 K3922001 5-二甲氨基萘-1-磺酰氯(2-8°C) 1g 1106元 2011/08/23 K3922002 二甲氨基萘-5-磺酰氯(+4℃) 5g 4974元 2011/04/16 D0005 丹磺酰氯(10%的丙酮溶液) Dansyl Chloride (10% in Acetone) 10ML 743元
  • F:10-21
  • MSDS 信息:5-(Dimethylamino)naphthalene-1-sulfonyl chloride(605-65-2).msds
  • 上游原料:盐酸 --> 乙酸乙酯 --> 乙醚 --> 石油醚 --> 碳酸氢钠 --> 硫酸二甲酯 --> 五氯化磷 --> 二氧化硅 --> 5-氨基-1-萘磺酸
  • 检测方法:HPLC,NMR
  • 敏感性:Moisture Sensitive
  • 用途一:有荧光性,用于分析。
  • TCI Shanghai:丹磺酰氯(10%的丙酮溶液) Dansyl Chloride (10% in Acetone)(605-65-2)

系列性分类


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