Pentafluoropropionic acid 五氟丙酸

CAS 422-64-0 MFCD00004170

化学结构图

422-64-0
SMILES: O=C(O)C(F)(F)C(F)(F)F

化学属性

Mol. FormulaC3HF5O2
Mol. Weight164.03
Boiling Point98°C(lit.)
TSCAT
Density1.561
Refractive indexn20/D 1.284(lit.)
Vapor Density~5.6 (vs air)
Vapor Pressure~40 mmHg ( 20 °C)
Flash PointNone
Stability对湿度敏感
Appearance colorless liq.

别名和识别编码

Chemical NamePentafluoropropionic acid
CAS Number422-64-0
Alfabeta NamePENTAFLUOROPROPIONICACID
MDL NumberMFCD00004170
Synonym Perfluoropropionic acid {LY} Perfluoropropionic acid {} {LY} Perfluoropropionic acid {} {} {LY} Perfluoropropionic acid {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Perfluoropropionic acid {} {} {} {} {} {} {} {} {} {} {} {}
EC Number207-021-6
Beilstein Registry Number1773387
PubChem Substance ID62356
Chemical Name Translation五氟丙酸
Reaxys-RN1773387
InChIKeyLRMSQVBRUNSOJL-UHFFFAOYSA-N
Wiswesser Line NotationQVXFFXFFF
LabNetwork Molecule IDLN00117745
InChIInChI=1S/C3HF5O2/c4-2(5,1(9)10)3(6,7)8/h(H,9,10)
Canonical SMILESO=C(O)C(F)(F)C(F)(F)F
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分类

  • {SNA} Alkyl Fluorinated Building Blocks, Building Blocks, C1 to C5, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Fluorinated Building Blocks, Organic Building Blocks, Organic Fluorinated Building Blocks, Other Fluorinated Organic Building Blocks, Trifluoromethyl
  • {uni_hamburg} no charge; carboxylic acid; 1fragment

产品应用

  • Pentafluoropropionic acid was used in the analysis of gentamicin with Gemini column by liquid chromatographic (LC) methods

相关文献及参考

  • Short: II/27B
  • Short: EINECS
  • Beilstein: 2,IV,739
  • The K salt is a convenient alternative to iodopentafluoroethane for the conversion of aryl bromides and iodides to their pentafluoroethyl derivatives, avoiding sealed-tube chemistry: Synth. Commun., 18, 965 (1988):

安全信息

Warnings HYGROSCOPIC, CORROSIVE
Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R20 Harmful by inhalation 吸入有害
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331
  • P301+P330+P331+P310
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P312
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P405 Store locked up. 上锁保管。
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSUF6475000
Packing GroupII
UN Number 3265 UN 3265 8/PG 2 UN3265
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H332 Harmful if inhaled 吸入有害
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 8 C
Hazard Class8
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 68400 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 2,299,1950

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15500 mg/m3/2H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 10(3),13,1966

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 21 gm/m3/2H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For

其他信息

  • 图谱信息:五氟丙酸(422-64-0)红外图谱(IR1) 五氟丙酸(422-64-0)质谱(MS) 五氟丙酸(422-64-0)核磁图( 13 CNMR)
  • 海关编码:29159080
  • 五氟丙酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P1125 五氟丙酸 Pentafluoropropionic Acid 25G 320元 2014/06/02 A5712 五氟丙酸(约0.5mol/L的水溶液)[用于液相色谱-质谱的离子对试剂] Pentafluoropropionic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS] 10ML 327元 2010/06/21 416920500 五氟丙酸 Pentafluoropropionic acid 97% 50 GR 1843元
  • Hazard Note:Corrosive
  • TSCA:T
  • F:3
  • Alfa Aesar:五氟丙酸,97% Pentafluoropropionic acid, 97%(422-64-0)
  • MSDS 信息:Perfluoropropionic acid(422-64-0).msds
  • 敏感性:Hygroscopic
  • MOL 文件:422-64-0.mol
  • Acros Organics:五氟丙酸 Pentafluoropropionic acid, 97%(422-64-0)
  • TCI Shanghai:五氟丙酸(约0.5mol/L的水溶液)[用于液相色谱-质谱的离子对试剂] Pentafluoropropionic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS](422-64-0)
  • Sigma Aldrich:422-64-0(sigmaaldrich)
  • 蒸气密度:~5.6 (vs air)
  • 蒸气压:~40 mm Hg ( 20 °C)

系列性分类