2,4,5-T solution 2,4,5-涕

CAS 93-76-5 MFCD00004301

化学结构图

93-76-5
SMILES: O=C(O)COc1cc(Cl)c(Cl)cc1Cl

化学属性

Mol. FormulaC8H5Cl3O3
Mol. Weight255
Melting Point154-158 °C
Flash Point2 °C
Appearance crystalline
Solubility难溶于水,易溶于多数有机溶剂。
Density1.592

别名和识别编码

Chemical Name2-(2,4,5-Trichlorophenoxy)acetic acid
CAS Number93-76-5
Synonym 2,4,5-Trichl Decamine 4T 2,4,5-涕酸 Acetic acid, (2,4,5-trichlorophenoxy)- {uni_hamburg} Spontox Phortox Weedone acide2,4,5-trichlorophenoxyacetique 2,4,5-T ACID Trioxon (2,4,5-Trichloor-fenoxy)-azijnzuur Envert-T Brush-off 445 low volatile brush killer Weedone 2,4,5-T Ded-weed lv-6 brush kil and t-5 brush kil WEEDONE Tributon Kwas 2,4,5-trojchlorofenoksyoctowy Fence rider 2'4'5-T {uni_hambur Arbokan Visko rhap low volatile ester Tippontormona 2,4,5-trichlorophenoxy acetic acid ,4,5-Trichlorophenoxyacetic acid (2,4,5-trichloro-phenoxy)-acetic aci Debroussaillant super concentre {uni 2,4,5-trichlorophenoxyacetiqueacide 2,4,5-三氯苯氧基乙酸 RCRA waste number U232 2,4,5-Trichlorophenoxyacetic acid Acide 2,4,5-trichloro phenoxyacetique Estercide T-2 and T-245 BCF-Bushki Reddon Estercide t-2 and t-245 Reddox {h Ded-weed brush killer 2,4,5-三氯苯氧基乙酸 溶液 2,4,5-三氯苯氧乙酸 Esteron 245 Dacamine (2,4,5-Trichlorophenoxy)acetic acid 2,4,5-Trichlorophenoxy-acetic acid 2-(2,4 Debroussaillant concentre (2,4,5-trichloor-fenoxy)-azijnzuur[qr] ethanoic acid, (2,4 Line rider Veon 245 (2,4,5-trichlorophenoxy)-aceticaci 2,4,5-Trichlorphenoxyessigsäure Dinoxol 2,4,5-T Weedar Fortex
MDL NumberMFCD00004301
PubChem Substance ID1480
EC Number200-835-2
Chemical Name Translation2,4,5-涕
Merck Number13,9111
Wiswesser Line NotationQV1OR BG DG EG
Beilstein Registry Number2055620
LabNetwork Molecule IDLN00193471
InChIInChI=1S/C8H5Cl3O3/c9-4-1-6(11)7(2-5(4)10)14-3-8(12)13/h1-2H,3H2,(H,12,13)
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards, Method and Regulation Specific, Oeko-Tex Standard 100, Pesticides, Phenoxy structure, Plant growth regulators, T, TA - TE, 农残和代谢标准品, 农残标准品, 灭草剂
  • {SNA} Alphabetical Index of Analyt
  • Auxins, Bioactive Small Molecules, Cell Biology, Plant Biotechnology, Plant Growth Regulators, Plant Tissue Culture, T
  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules,

产品应用

  • It is suitable for plant cell culture tested. Post-emergence herbicide.

相关文献及参考

  • Smith, J., et al.: Science, 203, 1090 (1979),
  • Merck: 14,9019
  • Estabrooks T, Browne R, Dong Z., 2,4,5-Trichlorophenoxyacetic acid promotes somatic embryogenesis in the rose cultivar "Livin' Easy" (Rosa sp.). Plant Cell Rep. 26 , 153-160, (2007) 摘要
  • Merck 14 ,9019
  • Wielandt AM, Vollrath V, et. al., Induction of the multispecific organic anion transporter (cMoat/mrp2) gene and biliary glutathione secretion by the herbicide 2,4,5-trichlorophenoxyacetic acid in the mouse liver. Biochem. J. 341 , 105-111, (1999) 摘要
  • Jouanneau JP, Lapous D, Guern J., In Plant Protoplasts, the Spontaneous Expression of Defense Reactions and the Responsiveness to Exogenous Elicitors Are under Auxin Control. Plant Physiol. 96 , 459-466, (1991) 摘要
  • Hirasawa E., Auxins induce α-amylase activity in pea cotyledons. Plant Physiol. 91 , 484-486, (1989) 摘要
  • Short: EINECS
  • Merck: 14,9019 Beilstein: 6,III,720
  • Short: IV/8A

安全信息

RTECSAJ8400000
GHS Symbol
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H312 Harmful in contact with skin 皮肤接触有害
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn;N F,Xn Xn,N,F
WGK Germany2
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Signal word Danger
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
  • R50/53
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36 Irritating to eyes 刺激眼睛
UN Number UN 2811 6.1/PG 3 2811
Packing GroupIII
Hazard Class6.1(b)
Storage condition 储存温度2-8℃ 充氩保存 0-6°C
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3379 mg/kg/33W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
   Skin and Appendages - tumors
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   33,626,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 215 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 242 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPZHAW Roczniki Panstwowego Zakladu Higieny.  (Ars Polona, POB 1001, 00-068
   Warsaw 1, Poland) V.1-    1950-  Volume(issue)/page/year: 31,373,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 310 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Behavioral - somnolence (general depressed activity)
   Liver - fatty liver degeneration
REFERENCE :
   AJVRAH American Journal of Veterinary Research.  (American Veterinary
   Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.1-    1940-
   Volume(issue)/page/year: 15,622,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PAREAQ Pharmacological Reviews.  (Williams & Wilkins, 428 E. Preston St.,
   Baltimore, MD 21202) V.1-    1949-  Volume(issue)/page/year: 14,225,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 425 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 65,83,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 1 nmol/plate
REFERENCE :
   MSERDS Microbiology Series.  (Marcel Dekker, 270 Madison Ave., New York, NY
   10016)  V.1-    1973-  Volume(issue)/page/year: 5,93,1981

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 250 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 65,83,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 35 mg/L
REFERENCE :
   ECBUDQ Ecological Bulletins

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm/15D
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 65,83,1979

TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 10 ppb
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   25,148,1995

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Fish - salmon Sperm
DOSE/DURATION           : 100 umol/L
REFERENCE :
   PYTCAS Phytochemistry.  An International Journal of Plant Biochemistry.
   (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-
      1961-  Volume(issue)/page/year: 11,3135,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 27600 ug/kg
SEX/DURATION            : female 10-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 2,708,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 60 mg/kg
SEX/DURATION            : female 10-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-160

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   PHBHA4 Physiology and Behavior.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1966-  Volume(issue)/page/year:
   9,357,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 200 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproduc

其他信息

  • MSDS 信息:2,4,5-涕(93-76-5).msds
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 类别:农药
  • 毒性分级:高毒
  • 急性毒性:口服- 大鼠 LD50: 300 毫克/公斤; 口服- 小鼠 LD50: 242 毫克/公斤
  • MOL 文件:93-76-5.mol
  • 图谱信息:2,4,5-三氯苯氧乙酸(93-76-5)红外图谱(IR1) 2,4,5-三氯苯氧乙酸(93-76-5)红外图谱(IR2) 2,4,5-三氯苯氧乙酸(93-76-5)质谱(MS) 2,4,5-三氯苯氧乙酸(93-76-5)核磁图( 1 HNMR)
  • Sigma Aldrich:93-76-5(sigmaaldrich)
  • color:off-white to yellow
  • 外观性质:无味白色结晶。
  • 灭火剂:干粉、泡沫、砂土
  • 可燃性危险特性:燃烧产生有毒氯化物气体
  • 职业标准:TWA 10 毫克/ 立方米

系列性分类


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